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ITGAX rabbit monoclonal antibody

  • Catalog # : H00003687-K
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  • Specification
  • Product Description:
  • Rabbit monoclonal antibody raised against a human ITGAX peptide using ARM Technology.
  • Immunogen:
  • A synthetic peptide of human ITGAX is used for rabbit immunization.
    Customer or Abnova will decide on the preferred peptide sequence.
  • Host:
  • Rabbit
  • Reactivity:
  • Human
  • Purification:
  • Protein A
  • Isotype:
  • IgG
  • Quality Control Testing:
  • Antibody reactive against human ITGAX peptide by ELISA and mammalian transfected lysate by Western Blot.
  • Storage Buffer:
  • In 1x PBS, pH 7.4
  • Storage Instruction:
  • Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
  • Note:
  • 1. Customer may provide cell or tissue lysate for antibody screening.
    2. Rabbit monoclonal antibody generated by ARM technology is amenable to antibody engineering including F(ab)2, IgG, scFv and different Fc and non-Fc conjugates per customer request.
  • Library Construction:
  • Non-fusion antibody library from rabbit spleen (ARM Technology).
  • Expression:
  • Overexpression vector and transfection into 293H cell line.
  • Deliverable:
  • Up to three rabbit IgG clones of 1 mg each will be delivered to customer.
  • Applications
  • ELISA
  • Application Image
  • Western Blot (Transfected lysate)
  • ELISA
  • Gene Information
  • Entrez GeneID:
  • 3687
  • GeneBank Accession#:
  • ITGAX
  • Gene Name:
  • ITGAX
  • Gene Alias:
  • CD11C,SLEB6
  • Gene Description:
  • integrin, alpha X (complement component 3 receptor 4 subunit)
  • Gene Summary:
  • This gene encodes the integrin alpha X chain protein. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This protein combines with the beta 2 chain (ITGB2) to form a leukocyte-specific integrin referred to as inactivated-C3b (iC3b) receptor 4 (CR4). The alpha X beta 2 complex seems to overlap the properties of the alpha M beta 2 integrin in the adherence of neutrophils and monocytes to stimulated endothelium cells, and in the phagocytosis of complement coated particles. [provided by RefSeq
  • Other Designations:
  • OTTHUMP00000163299,integrin alpha X,integrin, alpha X (antigen CD11C (p150), alpha polypeptide),leu M5, alpha subunit,leukocyte surface antigen p150,95, alpha subunit,myeloid membrane antigen, alpha subunit,p150 95 integrin alpha chain
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