ITGAE polyclonal antibody (A01)
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More Files
- More Functions
Western Blot detection against Immunogen (38.76 KDa) .
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Specification
Product Description
Mouse polyclonal antibody raised against a partial recombinant ITGAE.
Immunogen
ITGAE (NP_002199, 57 a.a. ~ 171 a.a) partial recombinant protein with GST tag.
Sequence
SPRTKRTPGPLHRCSLVQDEILCHPVEHVPIPKGRHRGVTVVRSHHGVLICIQVLVRRPHSLSSELTGTCSLLGPDLRPQAQANFFDLENLLDPDARVDTGDCYSNKEGGGEDDV
Host
Mouse
Reactivity
Human
Interspecies Antigen Sequence
Mouse (56); Rat (57)
Quality Control Testing
Antibody Reactive Against Recombinant Protein.
Western Blot detection against Immunogen (38.76 KDa) .
Storage Buffer
50 % glycerol
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Recombinant protein)
ELISA
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Gene Info — ITGAE
Entrez GeneID
3682GeneBank Accession#
NM_002208Protein Accession#
NP_002199Gene Name
ITGAE
Gene Alias
CD103, HUMINAE, MGC141996
Gene Description
integrin, alpha E (antigen CD103, human mucosal lymphocyte antigen 1; alpha polypeptide)
Omim ID
604682Gene Ontology
HyperlinkGene Summary
Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This gene encodes an I-domain-containing alpha integrin that undergoes post-translational cleavage in the extracellular domain, yielding disulfide-linked heavy and light chains. In combination with the beta 7 integrin, this protein forms the E-cadherin binding integrin known as the human mucosal lymphocyte-1 antigen. This protein is preferentially expressed in human intestinal intraepithelial lymphocytes (IEL), and in addition to a role in adhesion, it may serve as an accessory molecule for IEL activation. [provided by RefSeq
Other Designations
HML-1 antigen|antigen CD103, human mucosal lymphocyte antigen 1; alpha polypeptide|integrin alpha-IEL|integrin, alpha E
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Interactome
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Pathway
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Disease
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