ITGA5 rabbit monoclonal antibody
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Specification
Product Description
Rabbit monoclonal antibody raised against a human ITGA5 peptide using ARM Technology.
Immunogen
A synthetic peptide of human ITGA5 is used for rabbit immunization.
Customer or Abnova will decide on the preferred peptide sequence.Host
Rabbit
Library Construction
Non-fusion antibody library from rabbit spleen (ARM Technology).
Expression
Overexpression vector and transfection into 293H cell line.
Reactivity
Human
Purification
Protein A
Isotype
IgG
Quality Control Testing
Antibody reactive against human ITGA5 peptide by ELISA and mammalian transfected lysate by Western Blot.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
Deliverable
Up to three rabbit IgG clones of 100 ug each will be delivered to customer.
Note
1. Customer may provide cell or tissue lysate for antibody screening.
2. Rabbit monoclonal antibody generated by ARM technology is amenable to antibody engineering including F(ab)2, IgG, scFv and different Fc and non-Fc conjugates per customer request. -
Applications
Western Blot (Transfected lysate)
ELISA
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Gene Info — ITGA5
Entrez GeneID
3678GeneBank Accession#
ITGA5Gene Name
ITGA5
Gene Alias
CD49e, FNRA, VLA5A
Gene Description
integrin, alpha 5 (fibronectin receptor, alpha polypeptide)
Omim ID
135620Gene Ontology
HyperlinkGene Summary
The product of this gene belongs to the integrin alpha chain family. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This gene encodes the integrin alpha 5 chain. Alpha chain 5 undergoes post-translational cleavage in the extracellular domain to yield disulfide-linked light and heavy chains that join with beta 1 to form a fibronectin receptor. In addition to adhesion, integrins are known to participate in cell-surface mediated signalling. [provided by RefSeq
Other Designations
fibronectin receptor, alpha subunit|integrin alpha 5|very late activation protein 5, alpha subunit
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