ITGA4 monoclonal antibody (M01), clone 2C11
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Specification
Product Description
Mouse monoclonal antibody raised against a partial recombinant ITGA4.
Immunogen
ITGA4 (NP_000876, 98 a.a. ~ 207 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Sequence
RIGKNPGQTCEQLQLGSPNGEPCGKTCLEERDNQWLGVTLSRQPGENGSIVTCGHRWKNIFYIKNENKLPTGGCYGVPPDLRTELSKRIAPCYQDYVKKFGENFASCQAG
Host
Mouse
Reactivity
Human
Interspecies Antigen Sequence
Mouse (87); Rat (89)
Isotype
IgG1 Kappa
Quality Control Testing
Antibody Reactive Against Recombinant Protein.
Western Blot detection against Immunogen (37.84 KDa) .
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Cell lysate)
ITGA4 monoclonal antibody (M01), clone 2C11 Western Blot analysis of ITGA4 expression in Jurkat ( Cat # L017V1 ).Western Blot (Recombinant protein)
Sandwich ELISA (Recombinant protein)
Detection limit for recombinant GST tagged ITGA4 is approximately 0.3ng/ml as a capture antibody.ELISA
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Gene Info — ITGA4
Entrez GeneID
3676GeneBank Accession#
NM_000885Protein Accession#
NP_000876Gene Name
ITGA4
Gene Alias
CD49D, IA4, MGC90518
Gene Description
integrin, alpha 4 (antigen CD49D, alpha 4 subunit of VLA-4 receptor)
Omim ID
192975Gene Ontology
HyperlinkGene Summary
The product of this gene belongs to the integrin alpha chain family of proteins. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This gene encodes an alpha 4 chain. Unlike other integrin alpha chains, alpha 4 neither contains an I-domain, nor undergoes disulfide-linked cleavage. Alpha 4 chain associates with either beta 1 chain or beta 7 chain. [provided by RefSeq
Other Designations
269C wild type|antigen CD49D, alpha-4 subunit of VLA-4 receptor|integrin alpha 4|integrin alpha-4 subunit|very late activation protein 4 receptor, alpha 4 subunit
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Interactome
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Pathway
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Disease
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