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ISL1 Validated Chimera RNAi

  • Catalog # : H00003670-R01V
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  • Specification
  • Product Description:
  • Homo sapiens ISL1 transcription factor, LIM/homeodomain, (islet-1) (ISL1), mRNA.
  • Reactivity:
  • Human
  • Supplied Product:
  • DEPC water
  • Target Refseq:
  • NM_002202
  • Storage Instruction:
  • Store at -20°C, do not exceed 4 - 5 freeze-thaw cycles to ensure product integrity.
  • Note:
  • Position of the Chimera RNAi.

  • Publication Reference
  • Applications
  • RNAi Knockdown (Antibody validated)
  • RNAi Knockdown (Antibody validated)
  • Western blot analysis of ISL1 over-expressed 293 cell line, cotransfected with ISL1 Validated Chimera RNAi ( Cat # H00003670-R01V ) (Lane 2) or non-transfected control (Lane 1). Blot probed with ISL1 monoclonal antibody (M01), clone 1A3 (Cat # H00003670-M01 ). GAPDH ( 36.1 kDa ) used as specificity and loading control.
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  • Application Image
  • RNAi Knockdown (Antibody validated)
  • RNAi Knockdown (Antibody validated)
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  • Gene Information
  • Entrez GeneID:
  • 3670
  • Gene Name:
  • ISL1
  • Gene Alias:
  • Isl-1
  • Gene Description:
  • ISL LIM homeobox 1
  • Gene Summary:
  • This gene encodes a member of the LIM/homeodomain family of transcription factors. The encoded protein binds to the enhancer region of the insulin gene, among others, and may play an important role in regulating insulin gene expression. The encoded protein is central to the development of pancreatic cell lineages and may also be required for motor neuron generation. Mutations in this gene have been associated with maturity-onset diabetes of the young. [provided by RefSeq
  • Other Designations:
  • ISL1 transcription factor, LIM/homeodomain,islet-1
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