ISL1 monoclonal antibody (M01), clone 1A3

Catalog # H00003670-M01

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Size:100 ug
Price: USD $ 335.00
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Contact Info
  • +1-909-264-1399
    +1-909-992-0619
    Toll Free : +1-877-853-6098
  • +1-909-992-3401
Images
Western Blot (Cell lysate)
Application

Western Blot (Cell lysate)

ISL1 monoclonal antibody (M01), clone 1A3. Western Blot analysis of ISL1 expression in K-562(Cat # L009V1 ).

Western Blot (Cell lysate)
Application

Western Blot (Cell lysate)

ISL1 monoclonal antibody (M01), clone 1A3. Western Blot analysis of ISL1 expression in Hela S3 NE(Cat # L013V3 ).

Western Blot (Transfected lysate)
Application

Western Blot (Transfected lysate)

Western Blot analysis of ISL1 expression in transfected 293T cell line by ISL1 monoclonal antibody (M01), clone 1A3.

Lane 1: ISL1 transfected lysate(38.7 KDa).
Lane 2: Non-transfected lysate.

RNAi Knockdown (Antibody validated)
Application

RNAi Knockdown (Antibody validated)

Western blot analysis of ISL1 over-expressed 293 cell line, cotransfected with ISL1 Validated Chimera RNAi ( Cat # H00003670-R01V ) (Lane 2) or non-transfected control (Lane 1). Blot probed with ISL1 monoclonal antibody (M01), clone 1A3 (Cat # H00003670-M01 ). GAPDH ( 36.1 kDa ) used as specificity and loading control.

QC Test

Western Blot detection against Immunogen (36.41 KDa) .

  • Specification

    Product Description

    Mouse monoclonal antibody raised against a partial recombinant ISL1.

    Immunogen

    ISL1 (NP_002193, 63 a.a. ~ 159 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

    Sequence

    YCKRDYIRLYGIKCAKCSIGFSKNDFVMRARSKVYHIECFRCVACSRQLIPGDEFALREDGLFCRADHDVVERASLGAGDPLSPLHPARPLQMAAEP

    Host

    Mouse

    Reactivity

    Human

    Isotype

    IgG2a Kappa

    Quality Control Testing

    Antibody Reactive Against Recombinant Protein.

    Western Blot detection against Immunogen (36.41 KDa) .

    Storage Buffer

    In 1x PBS, pH 7.4

    Storage Instruction

    Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.

  • Applications

    Western Blot (Cell lysate)

    ISL1 monoclonal antibody (M01), clone 1A3. Western Blot analysis of ISL1 expression in K-562(Cat # L009V1 ).

    Western Blot (Cell lysate)

    ISL1 monoclonal antibody (M01), clone 1A3. Western Blot analysis of ISL1 expression in Hela S3 NE(Cat # L013V3 ).

    Western Blot (Transfected lysate)

    Western Blot analysis of ISL1 expression in transfected 293T cell line by ISL1 monoclonal antibody (M01), clone 1A3.

    Lane 1: ISL1 transfected lysate(38.7 KDa).
    Lane 2: Non-transfected lysate.

    Western Blot (Recombinant protein)

    ELISA

    RNAi Knockdown (Antibody validated)

    Western blot analysis of ISL1 over-expressed 293 cell line, cotransfected with ISL1 Validated Chimera RNAi ( Cat # H00003670-R01V ) (Lane 2) or non-transfected control (Lane 1). Blot probed with ISL1 monoclonal antibody (M01), clone 1A3 (Cat # H00003670-M01 ). GAPDH ( 36.1 kDa ) used as specificity and loading control.
  • Gene Info — ISL1

    Entrez GeneID

    3670

    GeneBank Accession#

    NM_002202

    Protein Accession#

    NP_002193

    Gene Name

    ISL1

    Gene Alias

    Isl-1

    Gene Description

    ISL LIM homeobox 1

    Omim ID

    600366

    Gene Ontology

    Hyperlink

    Gene Summary

    This gene encodes a member of the LIM/homeodomain family of transcription factors. The encoded protein binds to the enhancer region of the insulin gene, among others, and may play an important role in regulating insulin gene expression. The encoded protein is central to the development of pancreatic cell lineages and may also be required for motor neuron generation. Mutations in this gene have been associated with maturity-onset diabetes of the young. [provided by RefSeq

    Other Designations

    ISL1 transcription factor, LIM/homeodomain|islet-1

  • Interactome
  • Disease
Contact Info
  • +1-909-264-1399
    +1-909-992-0619
    Toll Free : +1-877-853-6098
  • +1-909-992-3401
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