PDX1 purified MaxPab rabbit polyclonal antibody (D01P)
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More Files
- More Functions
Western Blot (Tissue lysate)
PDX1 MaxPab rabbit polyclonal antibody. Western Blot analysis of PDX1 expression in human liver.
Western Blot (Tissue lysate)
PDX1 MaxPab rabbit polyclonal antibody. Western Blot analysis of PDX1 expression in mouse liver.
Western Blot (Transfected lysate)
Western Blot analysis of PDX1 expression in transfected 293T cell line (H00003651-T01) by PDX1 MaxPab polyclonal antibody.
Lane 1: PDX1 transfected lysate(31.13 KDa).
Lane 2: Non-transfected lysate.
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Specification
Product Description
Rabbit polyclonal antibody raised against a full-length human PDX1 protein.
Immunogen
PDX1 (AAI11593.1, 1 a.a. ~ 283 a.a) full-length human protein.
Sequence
MNGEEQYYAATQLYKDPCAFQRGPAPEFSASPPACLYMGRQPPPPPPHPFPGALGALEQGSPPDISPYEVPPLADDPAVAHLHHHLPAQLALPHPPAGPFPEGAEPGVLEEPNRVQLPFPWMKSTKAHAWKGQWAGGAYAAEPEENKRTRTAYTRAQLLELEKEFLFNKYISRPRRVELAVMLNLTERHIKIWFQNRRMKWKKEEDKKRGGGTAVGGGGVAEPEQDCAVTSGEELLALPPPPPPGGAVPPAAPVAAREGRLPPGLSASPQPSSVAPRRPQEPR
Host
Rabbit
Reactivity
Human, Mouse
Quality Control Testing
Antibody reactive against mammalian transfected lysate.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Tissue lysate)
PDX1 MaxPab rabbit polyclonal antibody. Western Blot analysis of PDX1 expression in human liver.Western Blot (Tissue lysate)
PDX1 MaxPab rabbit polyclonal antibody. Western Blot analysis of PDX1 expression in mouse liver.Western Blot (Transfected lysate)
Western Blot analysis of PDX1 expression in transfected 293T cell line (H00003651-T01) by PDX1 MaxPab polyclonal antibody.
Lane 1: PDX1 transfected lysate(31.13 KDa).
Lane 2: Non-transfected lysate.
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Gene Info — PDX1
Entrez GeneID
3651GeneBank Accession#
BC111592Protein Accession#
AAI11593.1Gene Name
PDX1
Gene Alias
GSF, IDX-1, IPF1, IUF1, MODY4, PDX-1, STF-1
Gene Description
pancreatic and duodenal homeobox 1
Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is a transcriptional activator of several genes, including insulin, somatostatin, glucokinase, islet amyloid polypeptide, and glucose transporter type 2. The encoded nuclear protein is involved in the early development of the pancreas and plays a major role in glucose-dependent regulation of insulin gene expression. Defects in this gene are a cause of pancreatic agenesis, which can lead to early-onset insulin-dependent diabetes mellitus (NIDDM), as well as maturity onset diabetes of the young type 4 (MODY4). [provided by RefSeq
Other Designations
OTTHUMP00000018174|glucose-sensitive factor|insulin promoter factor 1, homeodomain transcription factor|insulin upstream factor 1|pancreatic-duodenal homeobox factor 1|somatostatin transcription factor 1
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Interactome
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Pathway
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Disease
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