INSRR monoclonal antibody (M01), clone 6E6
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Specification
Product Description
Mouse monoclonal antibody raised against a partial recombinant INSRR.
Immunogen
INSRR (NP_055030, 651 a.a. ~ 760 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Sequence
LYLNDYCHRGLRLPTSNNDPRFDGEDGDPEAEMESDCCPCQHPPPGQVLPPLEAQEASFQKKFENFLHNAITIPISPWKVTSINKSPQRDSGRHRRAAGPLRLGGNSSDF
Host
Mouse
Reactivity
Human
Interspecies Antigen Sequence
Mouse (77); Rat (76)
Isotype
IgG1 Kappa
Quality Control Testing
Antibody Reactive Against Recombinant Protein.
Western Blot detection against Immunogen (37.73 KDa) .
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Cell lysate)
INSRR monoclonal antibody (M01), clone 6E6 Western Blot analysis of INSRR expression in HeLa ( Cat # L013V1 ).Western Blot (Recombinant protein)
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunoperoxidase of monoclonal antibody to INSRR on formalin-fixed paraffin-embedded human esophagus. [antibody concentration 1 ug/ml]Sandwich ELISA (Recombinant protein)
Detection limit for recombinant GST tagged INSRR is approximately 0.03ng/ml as a capture antibody.ELISA
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Gene Info — INSRR
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Interactome
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Pathway
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Disease
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Publication Reference
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IRR is involved in glucose-induced endocytosis after insulin secretion.
Yamaoka M, Terabayashi T, Nishioka T, Kaibuchi K, Ishikawa T, Ishizaki T, Kimura T.
Journal of Pharmacological Sciences 2019 Jul; 140(3):300.
Application:WB, Mouse, MIN6 cells.
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IRR is involved in glucose-induced endocytosis after insulin secretion.
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