INPP5B 293T Cell Transient Overexpression Lysate(Denatured)
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More Files
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SDS-PAGE Gel
INPP5B transfected lysate.
Western Blot
Lane 1: INPP5B transfected lysate ( 82.39 KDa)
Lane 2: Non-transfected lysate.
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Specification
Transfected Cell Line
293T
Plasmid
pCMV-INPP5B full-length
Host
Human
Theoretical MW (kDa)
82.39
Interspecies Antigen Sequence
Mouse (79); Rat (86)
Quality Control Testing
Transient overexpression cell lysate was tested with Anti-INPP5B antibody (H00003633-B01) by Western Blots.
SDS-PAGE Gel
INPP5B transfected lysate.
Western Blot
Lane 1: INPP5B transfected lysate ( 82.39 KDa)
Lane 2: Non-transfected lysate.Storage Buffer
1X Sample Buffer (50 mM Tris-HCl, 2% SDS, 10% glycerol, 300 mM 2-mercaptoethanol, 0.01% Bromophenol blue)
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot
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Gene Info — INPP5B
Entrez GeneID
3633GeneBank Accession#
NM_005540.1Protein Accession#
AAH58932.1Gene Name
INPP5B
Gene Alias
5PTase, MGC65156, MGC71303
Gene Description
inositol polyphosphate-5-phosphatase, 75kDa
Omim ID
147264Gene Ontology
HyperlinkGene Summary
Cellular calcium signaling is controlled by the production of inositol phosphates (IPs) by phospholipase C in response to extracellular signals. The IP signaling molecules are inactivated by a family of inositol polyphosphate-5-phosphatases (5-phosphatases). This gene encodes the type II 5-phosphatase. The protein is localized to the cytosol and mitochondria, and associates with membranes through an isoprenyl modification near the C-terminus. Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of some of these variants has not been determined. [provided by RefSeq
Other Designations
OTTHUMP00000004726|phosphoinositide 5-phosphatase|type II inositol-1,4,5-trisphosphate 5-phosphatase
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Interactome
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Pathway
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Disease
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