ING2 (Human) Recombinant Protein (P01)
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More Files
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Specification
Product Description
Human ING2 full-length ORF ( AAH30128, 1 a.a. - 280 a.a.) recombinant protein with GST-tag at N-terminal.
Sequence
MLGQQQQQLYSSAALLTGERSRLLTCYVQDYLECVESLPHDMQRNVSVLRELDNKYQETLKEIDDVYEKYKKEDDLNQKKRLQQLLQRALINSQELGDEKIQIVTQMLELVENRARQMELHSQCFQDPAESERASDKAKMDSSQPERSSRRPRRQRTSESRDLCHMANGIEDCDDQPPKEKKSKSAKKKKRSKAKQEREASPVEFAIDPNEPTYCLCNQVSYGEMIGCDNEQCPIEWFHFSCVSLTYKPKGKWYCPKCRGDNEKTMGKSTEKTKKDRRSR
Host
Wheat Germ (in vitro)
Theoretical MW (kDa)
56.54
Interspecies Antigen Sequence
Mouse (96); Rat (96)
Preparation Method
Purification
Glutathione Sepharose 4 Fast Flow
Quality Control Testing
12.5% SDS-PAGE Stained with Coomassie Blue.
Storage Buffer
50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
Note
Best use within three months from the date of receipt of this protein.
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Applications
Enzyme-linked Immunoabsorbent Assay
Western Blot (Recombinant protein)
Antibody Production
Protein Array
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Gene Info — ING2
Entrez GeneID
3622GeneBank Accession#
BC030128Protein Accession#
AAH30128Gene Name
ING2
Gene Alias
ING1L, p33ING2
Gene Description
inhibitor of growth family, member 2
Omim ID
604215Gene Ontology
HyperlinkGene Summary
This gene is a member of the inhibitor of growth (ING) family. Members of the ING family associate with and modulate the activity of histone acetyltransferase (HAT) and histone deacetylase (HDAC) complexes and function in DNA repair and apoptosis. [provided by RefSeq
Other Designations
inhibitor of growth 1-like|inhibitor of growth family, member 1-like
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Interactome
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Publication Reference
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Sumoylation of ING2 regulates the transcription mediated by Sin3A.
Ythier D, Larrieu D, Binet R, Binda O, Brambilla C, Gazzeri S, Pedeux R.
Oncogene 2010 Nov; 29(44):5946.
Application：Func, WB-Re, Recombinant protein.
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Sumoylation of ING2 regulates the transcription mediated by Sin3A.
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