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ING1 rabbit monoclonal antibody

  • Catalog # : H00003621-K
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  • Specification
  • Product Description:
  • Rabbit monoclonal antibody raised against a human ING1 peptide using ARM Technology.
  • Immunogen:
  • A synthetic peptide of human ING1 is used for rabbit immunization.
    Customer or Abnova will decide on the preferred peptide sequence.
  • Host:
  • Rabbit
  • Reactivity:
  • Human
  • Purification:
  • Protein A
  • Isotype:
  • IgG
  • Quality Control Testing:
  • Antibody reactive against human ING1 peptide by ELISA and mammalian transfected lysate by Western Blot.
  • Storage Buffer:
  • In 1x PBS, pH 7.4
  • Storage Instruction:
  • Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
  • Note:
  • 1. Customer may provide cell or tissue lysate for antibody screening.
    2. Rabbit monoclonal antibody generated by ARM technology is amenable to antibody engineering including F(ab)2, IgG, scFv and different Fc and non-Fc conjugates per customer request.
  • Library Construction:
  • Non-fusion antibody library from rabbit spleen (ARM Technology).
  • Expression:
  • Overexpression vector and transfection into 293H cell line.
  • Deliverable:
  • Up to three rabbit IgG clones of 1 mg each will be delivered to customer.
  • Applications
  • ELISA
  • Application Image
  • Western Blot (Transfected lysate)
  • ELISA
  • Gene Information
  • Entrez GeneID:
  • 3621
  • GeneBank Accession#:
  • ING1
  • Gene Name:
  • ING1
  • Gene Alias:
  • p24ING1c,p33,p33ING1,p33ING1b,p47,p47ING1a
  • Gene Description:
  • inhibitor of growth family, member 1
  • Gene Summary:
  • This gene encodes a tumor suppressor protein that can induce cell growth arrest and apoptosis. The encoded protein is a nuclear protein that physically interacts with the tumor suppressor protein TP53 and is a component of the p53 signaling pathway. Reduced expression and rearrangement of this gene have been detected in various cancers. Multiple alternatively spliced transcript variants encoding distinct isoforms have been reported. [provided by RefSeq
  • Other Designations:
  • OTTHUMP00000018703,OTTHUMP00000018704,OTTHUMP00000018705,OTTHUMP00000018706,growth inhibitor ING1,growth inhibitory protein ING1,inhibitor of growth 1,tumor suppressor ING1
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