Immunoprecipitation of ING1 transfected lysate using anti-ING1 MaxPab rabbit polyclonal antibody and Protein A Magnetic Bead (U0007), and immunoblotted with ING1 MaxPab mouse polyclonal antibody (B01) (H00003621-B01).
This gene encodes a tumor suppressor protein that can induce cell growth arrest and apoptosis. The encoded protein is a nuclear protein that physically interacts with the tumor suppressor protein TP53 and is a component of the p53 signaling pathway. Reduced expression and rearrangement of this gene have been detected in various cancers. Multiple alternatively spliced transcript variants encoding distinct isoforms have been reported. [provided by RefSeq
OTTHUMP00000018703,OTTHUMP00000018704,OTTHUMP00000018705,OTTHUMP00000018706,growth inhibitor ING1,growth inhibitory protein ING1,inhibitor of growth 1,tumor suppressor ING1