ILF2 (Human) Recombinant Protein (P01)
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More Files
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Specification
Product Description
Human ILF2 full-length ORF ( NP_004506.2, 1 a.a. - 390 a.a.) recombinant protein with GST-tag at N-terminal.
Sequence
MRGDRGRGRGGRFGSRGGPGGGFRPFVPHIPFDFYLCEMAFPRVKPAPDETSFSEALLKRNQDLAPNSAEQASILSLVTKINNVIDNLIVAPGTFEVQIEEVRQVGSYKKGTMTTGHNVADLVVILKILPTLEAVAALGNKVVESLRAQDPSEVLTMLTNETGFEISSSDATVKILITTVPPNLRKLDPELHLDIKVLQSALAAIRHARWFEENASQSTVKVLIRLLKDLRIRFPGFEPLTPWILDLLGHYAVMNNPTRQPLALNVAYRRCLQILAAGLFLPGSVGITDPCESGNFRVHTVMTLEQQDMVCYTAQTLVRILSHGGFRKILGQEGDASYLASEISTWDGVIVTPSEKAYEKPPEKKEGEEEEENTEEPPQGEEEESMETQE
Host
Wheat Germ (in vitro)
Theoretical MW (kDa)
69.5
Interspecies Antigen Sequence
Mouse (100)
Preparation Method
Purification
Glutathione Sepharose 4 Fast Flow
Quality Control Testing
12.5% SDS-PAGE Stained with Coomassie Blue.
Storage Buffer
50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
Note
Best use within three months from the date of receipt of this protein.
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Applications
Enzyme-linked Immunoabsorbent Assay
Western Blot (Recombinant protein)
Antibody Production
Protein Array
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Gene Info — ILF2
Entrez GeneID
3608GeneBank Accession#
NM_004515.2Protein Accession#
NP_004506.2Gene Name
ILF2
Gene Alias
MGC8391, NF45, PRO3063
Gene Description
interleukin enhancer binding factor 2, 45kDa
Omim ID
603181Gene Ontology
HyperlinkGene Summary
Nuclear factor of activated T-cells (NFAT) is a transcription factor required for T-cell expression of the interleukin 2 gene. NFAT binds to a sequence in the interleukin 2 gene enhancer known as the antigen receptor response element 2. In addition, NFAT can bind RNA and is an essential component for encapsidation and protein priming of hepatitis B viral polymerase. NFAT is a heterodimer of 45 kDa and 90 kDa proteins, the smaller of which is the product of this gene. The encoded protein binds strongly to the 90 kDa protein and stimulates its ability to enhance gene expression. [provided by RefSeq
Other Designations
interleukin enhancer binding factor 2|nuclear factor of activated T-cells, 45-kDa
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Interactome
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Publication Reference
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ILF2 Directly Binds and Stabilizes CREB to Stimulate Malignant Phenotypes of Liver Cancer Cells.
Du H, Le Y, Sun F, Li K, Xu Y.
Analytical Cellular Pathology (Amsterdam) 2019 Feb; 2019:1575031.
Application：IP, Human, Bel-7402, SMMC-7721 cells.
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ILF2 Directly Binds and Stabilizes CREB to Stimulate Malignant Phenotypes of Liver Cancer Cells.
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