IL13RA1 rabbit monoclonal antibody
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Specification
Product Description
Rabbit monoclonal antibody raised against a human IL13RA1 peptide using ARM Technology.
Immunogen
A synthetic peptide of human IL13RA1 is used for rabbit immunization.
Customer or Abnova will decide on the preferred peptide sequence.Host
Rabbit
Library Construction
Non-fusion antibody library from rabbit spleen (ARM Technology).
Expression
Overexpression vector and transfection into 293H cell line.
Reactivity
Human
Purification
Protein A
Isotype
IgG
Quality Control Testing
Antibody reactive against human IL13RA1 peptide by ELISA and mammalian transfected lysate by Western Blot.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
Deliverable
Up to three rabbit IgG clones of 100 ug each will be delivered to customer.
Note
1. Customer may provide cell or tissue lysate for antibody screening.
2. Rabbit monoclonal antibody generated by ARM technology is amenable to antibody engineering including F(ab)2, IgG, scFv and different Fc and non-Fc conjugates per customer request. -
Applications
Western Blot (Transfected lysate)
ELISA
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Gene Info — IL13RA1
Entrez GeneID
3597GeneBank Accession#
IL13RA1Gene Name
IL13RA1
Gene Alias
CD213A1, IL-13Ra, NR4
Gene Description
interleukin 13 receptor, alpha 1
Omim ID
300119Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is a subunit of the interleukin 13 receptor. This subunit forms a receptor complex with IL4 receptor alpha, a subunit shared by IL13 and IL4 receptors. This subunit serves as a primary IL13-binding subunit of the IL13 receptor, and may also be a component of IL4 receptors. This protein has been shown to bind tyrosine kinase TYK2, and thus may mediate the signaling processes that lead to the activation of JAK1, STAT3 and STAT6 induced by IL13 and IL4. [provided by RefSeq
Other Designations
CD213a1 antigen|IL13 receptor alpha-1 chain|OTTHUMP00000023890|bB128O4.2.1 (interleukin 13 receptor, alpha 1)
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