IL12RB2 293T Cell Transient Overexpression Lysate(Denatured)
* The price is valid only in USA. Please select country.
-
More Files
- More Functions
-
Specification
Transfected Cell Line
293T
Plasmid
pCMV-IL12RB2 full-length
Host
Human
Theoretical MW (kDa)
97.1
Quality Control Testing
Transient overexpression cell lysate was tested with Anti-IL12RB2 antibody (H00003595-B01) by Western Blots.
SDS-PAGE Gel
IL12RB2 transfected lysate.
Western Blot
Lane 1: IL12RB2 transfected lysate ( 97.1 KDa)
Lane 2: Non-transfected lysate.Storage Buffer
1X Sample Buffer (50 mM Tris-HCl, 2% SDS, 10% glycerol, 300 mM 2-mercaptoethanol, 0.01% Bromophenol blue)
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
-
Applications
Western Blot
-
Gene Info — IL12RB2
Entrez GeneID
3595GeneBank Accession#
NM_001559Protein Accession#
NP_001550Gene Name
IL12RB2
Gene Alias
-
Gene Description
interleukin 12 receptor, beta 2
Omim ID
601642Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is a type I transmembrane protein identified as a subunit of the interleukin 12 receptor complex. The coexpression of this and IL12RB1 proteins was shown to lead to the formation of high-affinity IL12 binding sites and reconstitution of IL12 dependent signaling. The expression of this gene is up-regulated by interferon gamma in Th1 cells, and plays a role in Th1 cell differentiation. The up-regulation of this gene is found to be associated with a number of infectious diseases, such as Crohn's disease and leprosy, which is thought to contribute to the inflammatory response and host defense. [provided by RefSeq
Other Designations
IL-12 receptor beta 2|OTTHUMP00000010662|interleukin-12 receptor beta-2 chain
-
Interactome
-
Pathway
-
Disease
- +1-909-264-1399
+1-909-992-0619
Toll Free : +1-877-853-6098 - +1-909-992-3401
- sales@abnova.com