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IL12RB1 (Human) IP-WB Antibody Pair

  • Catalog # : H00003594-PW1
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  • Specification
  • Product Description:
  • This IP-WB antibody pair set comes with one antibody for immunoprecipitation and another to detect the precipitated protein in western blot.
  • Reactivity:
  • Human
  • Quality Control Testing:
  • Immunoprecipitation-Western Blot (IP-WB)

    QC Testing of H00003594-PW1
    Immunoprecipitation of IL12RB1 transfected lysate using rabbit polyclonal anti-IL12RB1 and Protein A Magnetic Bead (U0007), and immunoblotted with mouse polyclonal anti-IL12RB1.
  • Supplied Product:
  • Antibody pair set content:
    1. Antibody pair for IP: rabbit polyclonal anti-IL12RB1 (300 ul)
    2. Antibody pair for WB: mouse polyclonal anti-IL12RB1 (50 ul)
  • Storage Instruction:
  • Store reagents of the antibody pair set at -20°C or lower. Please aliquot to avoid repeated freeze thaw cycle. Reagents should be returned to -20°C storage immediately after use.
  • Applications
  • Application Image
  • Immunoprecipitation-Western Blot
  • Gene Information
  • Entrez GeneID:
  • 3594
  • Gene Name:
  • IL12RB1
  • Gene Alias:
  • CD212,IL-12R-BETA1,IL12RB,MGC34454
  • Gene Description:
  • interleukin 12 receptor, beta 1
  • Gene Summary:
  • The protein encoded by this gene is a type I transmembrane protein that belongs to the hemopoietin receptor superfamily. This protein binds to interleukine 12 (IL12) with a low affinity, and is thought to be a part of IL12 receptor complex. This protein forms a disulfide-linked oligomer, which is required for its IL12 binding activity. The coexpression of this and IL12RB2 proteins was shown to lead to the formation of high-affinity IL12 binding sites and reconstitution of IL12 dependent signaling. The lack of expression of this gene was found to result in the immunodeficiency of patients with severe mycobacterial and Salmonella infections. Two alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported. [provided by RefSeq
  • Other Designations:
  • IL-12 receptor beta component,interleukin-12 receptor beta-1 chain
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