IL11 monoclonal antibody (M17), clone 1F1
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Specification
Product Description
Mouse monoclonal antibody raised against a partial recombinant IL11.
Immunogen
IL11 (NP_000632.1, 25 a.a. ~ 74 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Sequence
PPGPPRVSPDPRAELDSTVLLTRSLLADTRQLAAQLRDKFPADGDHNLDS
Host
Mouse
Reactivity
Human
Isotype
IgG2a Kappa
Quality Control Testing
Antibody Reactive Against Recombinant Protein.
Western Blot detection against Immunogen (31.24 KDa) .
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Recombinant protein)
Sandwich ELISA (Recombinant protein)
Detection limit for recombinant GST tagged IL11 is approximately 0.3ng/ml as a capture antibody.ELISA
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Gene Info — IL11
Entrez GeneID
3589GeneBank Accession#
NM_000641Protein Accession#
NP_000632.1Gene Name
IL11
Gene Alias
AGIF, IL-11
Gene Description
interleukin 11
Omim ID
147681Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is a member of the gp130 family of cytokines. These cytokines drive the assembly of multisubunit receptor complexes, all of which contain at least one molecule of the transmembrane signaling receptor IL6ST (gp130). This cytokine is shown to stimulate the T-cell-dependent development of immunoglobulin-producing B cells. It is also found to support the proliferation of hematopoietic stem cells and megakaryocyte progenitor cells. [provided by RefSeq
Other Designations
adipogenesis inhibitory factor|oprelvekin
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Interactome
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Pathway
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Disease
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