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IL6ST Pre-design Chimera RNAi

  • Catalog # : H00003572-R04
  • Visit Frequency :
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  • Specification
  • Product Description:
  • Homo sapiens interleukin 6 signal transducer (gp130, oncostatin M receptor) (IL6ST), transcript variant 2, mRNA.
  • Reactivity:
  • Human
  • Supplied Product:
  • DEPC water
  • Target Refseq:
  • NM_175767
  • Target Region:
  • 3' Untranslated Region (3'UTR)
  • Storage Instruction:
  • Store at -20°C, do not exceed 4 - 5 freeze-thaw cycles to ensure product integrity.
  • Note:
  • Position of the Chimera RNAi.
    The related RNAi products listed below were designed from different accesion number but sharing the same RNAi sequence.

  • Publication Reference
  • Applications
  • RNAi Knockdown
  • Application Image
  • RNAi Knockdown
  • Gene Information
  • Entrez GeneID:
  • 3572
  • Gene Name:
  • IL6ST
  • Gene Alias:
  • CD130,CDw130,GP130,GP130-RAPS,IL6R-beta
  • Gene Description:
  • interleukin 6 signal transducer (gp130, oncostatin M receptor)
  • Gene Summary:
  • The protein encoded by this gene is a signal transducer shared by many cytokines, including interleukin 6 (IL6), ciliary neurotrophic factor (CNTF), leukemia inhibitory factor (LIF), and oncostatin M (OSM). This protein functions as a part of the cytokine receptor complex. The activation of this protein is dependent upon the binding of cytokines to their receptors. vIL6, a protein related to IL6 and encoded by the Kaposi sarcoma-associated herpesvirus, can bypass the interleukin 6 receptor (IL6R) and directly activate this protein. Knockout studies in mice suggested a critical role of the gene encoding this protein in regulating myocyte apoptosis. Alternatively spliced transcript variants encoding distinct isoforms have been described. [provided by RefSeq
  • Other Designations:
  • CD130 antigen,IL6ST nirs variant 3,OTTHUMP00000122545,gp130 of the rheumatoid arthritis antigenic peptide-bearing soluble form,gp130 transducer chain,interleukin 6 signal transducer,interleukin receptor beta chain,membrane glycoprotein gp130,oncostatin M
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