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Last updated: 2016/11/27
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IL6ST polyclonal antibody (A01)

  • Catalog # : H00003572-A01
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  • Specification
  • Product Description:
  • Mouse polyclonal antibody raised against a partial recombinant IL6ST.
  • Immunogen:
  • IL6ST (NP_002175, 23 a.a. ~ 122 a.a) partial recombinant protein with GST tag.
  • Sequence:
  • ELLDPCGYISPESPVVQLHSNFTAVCVLKEKCMDYFHVNANYIVWKTNHFTIPKEQYTIINRTASSVTFTDIASLNIQLTCNILTFGQLEQNVYGITIIS
  • Host:
  • Mouse
  • Reactivity:
  • Human
  • Quality Control Testing:
  • Antibody Reactive Against Recombinant Protein.

    QC Testing of H00003572-A01
    Western Blot detection against Immunogen (37.11 KDa) .
  • Storage Buffer:
  • 50 % glycerol
  • Storage Instruction:
  • Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
  • Applications
  • ELISA
  • Application Image
  • Western Blot (Recombinant protein)
  • ELISA
  • Gene Information
  • Entrez GeneID:
  • 3572
  • Gene Name:
  • IL6ST
  • Gene Alias:
  • CD130,CDw130,GP130,GP130-RAPS,IL6R-beta
  • Gene Description:
  • interleukin 6 signal transducer (gp130, oncostatin M receptor)
  • Gene Summary:
  • The protein encoded by this gene is a signal transducer shared by many cytokines, including interleukin 6 (IL6), ciliary neurotrophic factor (CNTF), leukemia inhibitory factor (LIF), and oncostatin M (OSM). This protein functions as a part of the cytokine receptor complex. The activation of this protein is dependent upon the binding of cytokines to their receptors. vIL6, a protein related to IL6 and encoded by the Kaposi sarcoma-associated herpesvirus, can bypass the interleukin 6 receptor (IL6R) and directly activate this protein. Knockout studies in mice suggested a critical role of the gene encoding this protein in regulating myocyte apoptosis. Alternatively spliced transcript variants encoding distinct isoforms have been described. [provided by RefSeq
  • Other Designations:
  • CD130 antigen,IL6ST nirs variant 3,OTTHUMP00000122545,gp130 of the rheumatoid arthritis antigenic peptide-bearing soluble form,gp130 transducer chain,interleukin 6 signal transducer,interleukin receptor beta chain,membrane glycoprotein gp130,oncostatin M
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