IL6R 293T Cell Transient Overexpression Lysate(Denatured)
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More Files
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Specification
Transfected Cell Line
293T
Plasmid
pCMV-IL6R full-length
Host
Human
Theoretical MW (kDa)
51.59
Quality Control Testing
Transient overexpression cell lysate was tested with Anti-IL6R antibody (H00003570-B01) by Western Blots.
SDS-PAGE Gel
IL6R transfected lysate.
Western Blot
Lane 1: IL6R transfected lysate ( 51.59 KDa)
Lane 2: Non-transfected lysate.Storage Buffer
1X Sample Buffer (50 mM Tris-HCl, 2% SDS, 10% glycerol, 300 mM 2-mercaptoethanol, 0.01% Bromophenol blue)
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot
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Gene Info — IL6R
Entrez GeneID
3570GeneBank Accession#
NM_000565Protein Accession#
NP_000556Gene Name
IL6R
Gene Alias
CD126, IL-6R-1, IL-6R-alpha, IL6RA, MGC104991
Gene Description
interleukin 6 receptor
Omim ID
147880Gene Ontology
HyperlinkGene Summary
Interleukin 6 (IL6) is a potent pleiotropic cytokine that regulates cell growth and differentiation and plays an important role in immune response. The protein encoded by this gene is a subunit of the receptor complex for IL6. The IL6 receptor is a protein complex consisting of this protein and interleukin 6 signal transducer (IL6ST/GP130/IL6-beta), a receptor subunit also shared by many other cytokines. Dysregulated production of IL6 and this receptor are implicated in the pathogenesis of many diseases, such as multiple myeloma, autoimmune diseases and prostate cancer. Alternatively spliced transcript variants encoding distinct isoforms have been reported. [provided by RefSeq
Other Designations
CD126 antigen|OTTHUMP00000034320|interleukin 6 receptor alpha subunit
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