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Last updated: 2017/7/16

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IL5RA rabbit monoclonal antibody

  • Catalog # : H00003568-K
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  • Specification
  • Product Description:
  • Rabbit monoclonal antibody raised against a human IL5RA peptide using ARM Technology.
  • Immunogen:
  • A synthetic peptide of human IL5RA is used for rabbit immunization.
    Customer or Abnova will decide on the preferred peptide sequence.
  • Host:
  • Rabbit
  • Reactivity:
  • Human
  • Purification:
  • Protein A
  • Isotype:
  • IgG
  • Quality Control Testing:
  • Antibody reactive against human IL5RA peptide by ELISA and mammalian transfected lysate by Western Blot.
  • Storage Buffer:
  • In 1x PBS, pH 7.4
  • Storage Instruction:
  • Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
  • Note:
  • 1. Customer may provide cell or tissue lysate for antibody screening.
    2. Rabbit monoclonal antibody generated by ARM technology is amenable to antibody engineering including F(ab)2, IgG, scFv and different Fc and non-Fc conjugates per customer request.
  • Library Construction:
  • Non-fusion antibody library from rabbit spleen (ARM Technology).
  • Expression:
  • Overexpression vector and transfection into 293H cell line.
  • Deliverable:
  • Up to three rabbit IgG clones of 1 mg each will be delivered to customer.
  • Applications
  • ELISA
  • Application Image
  • Western Blot (Transfected lysate)
  • ELISA
  • Gene Information
  • Entrez GeneID:
  • 3568
  • GeneBank Accession#:
  • IL5RA
  • Gene Name:
  • IL5RA
  • Gene Alias:
  • CD125,CDw125,HSIL5R3,IL5R,MGC26560
  • Gene Description:
  • interleukin 5 receptor, alpha
  • Gene Summary:
  • The protein encoded by this gene is an interleukin 5 specific subunit of a heterodimeric cytokine receptor. The receptor is comprised of a ligand specific alpha subunit and a signal transducing beta subunit shared by the receptors for interleukin 3 (IL3), colony stimulating factor 2 (CSF2/GM-CSF), and interleukin 5 (IL5). The binding of this protein to IL5 depends on the beta subunit. The beta subunit is activated by the ligand binding, and is required for the biological activities of IL5. This protein has been found to interact with syndecan binding protein (syntenin), which is required for IL5 mediated activation of the transcription factor SOX4. Six alternatively spliced transcript variants encoding three distinct isoforms have been reported. [provided by RefSeq
  • Other Designations:
  • CD125 antigen,OTTHUMP00000115257,OTTHUMP00000115373,interleukin 5 receptor type 3,interleukin-5 receptor alpha chain,interleukin-5 receptor alpha subunit
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