IL5RA purified MaxPab mouse polyclonal antibody (B01P)
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More Files
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Specification
Product Description
Mouse polyclonal antibody raised against a full-length human IL5RA protein.
Immunogen
IL5RA (NP_783852.1, 1 a.a. ~ 335 a.a) full-length human protein.
Sequence
MIIVAHVLLILLGATEILQADLLPDEKISLLPPVNFTIKVTGLAQVLLQWKPNPDQEQRNVNLEYQVKINAPKEDDYETRITESKCVTILHKGFSASVRTILQNDHSLLASSWASAELHAPPGSPGTSIVNLTCTTNTTEDNYSRLRSYQVSLHCTWLVGTDAPEDTQYFLYYRYGSWTEECQEYSKDTLGRNIACWFPRTFILSKGRDWLAVLVNGSSKHSAIRPFDQLFALHAIDQINPPLNVTAEIEGTRLSIQWEKPVSAFPIHCFDYEVKIHNTRNGYLQIEKLMTNAFISIIDDLSKYDVQVRAAVSSMCREAGLWSEWSQPIYVGFSR
Host
Mouse
Reactivity
Human
Interspecies Antigen Sequence
Mouse (72); Rat (71)
Quality Control Testing
Antibody reactive against mammalian transfected lysate.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Transfected lysate)
Western Blot analysis of IL5RA expression in transfected 293T cell line (H00003568-T01) by IL5RA MaxPab polyclonal antibody.
Lane 1: IL5RA transfected lysate(38.00 KDa).
Lane 2: Non-transfected lysate.
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Gene Info — IL5RA
Entrez GeneID
3568GeneBank Accession#
NM_175725.1Protein Accession#
NP_783852.1Gene Name
IL5RA
Gene Alias
CD125, CDw125, HSIL5R3, IL5R, MGC26560
Gene Description
interleukin 5 receptor, alpha
Omim ID
147851Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is an interleukin 5 specific subunit of a heterodimeric cytokine receptor. The receptor is comprised of a ligand specific alpha subunit and a signal transducing beta subunit shared by the receptors for interleukin 3 (IL3), colony stimulating factor 2 (CSF2/GM-CSF), and interleukin 5 (IL5). The binding of this protein to IL5 depends on the beta subunit. The beta subunit is activated by the ligand binding, and is required for the biological activities of IL5. This protein has been found to interact with syndecan binding protein (syntenin), which is required for IL5 mediated activation of the transcription factor SOX4. Six alternatively spliced transcript variants encoding three distinct isoforms have been reported. [provided by RefSeq
Other Designations
CD125 antigen|OTTHUMP00000115257|OTTHUMP00000115373|interleukin 5 receptor type 3|interleukin-5 receptor alpha chain|interleukin-5 receptor alpha subunit
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Interactome
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Disease
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