IL4R (Human) Matched Antibody Pair
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Specification
Product Description
This antibody pair set comes with a matched antibody pair to detect and quantify the protein level of human IL4R.
Reactivity
Human
Quality Control Testing
Standard curve using recombinant protein ( H00003566-Q01 ) as an analyte.
Sandwich ELISA detection sensitivity ranging from 0.3 ng/ml to 100 ng/ml.
Supplied Product
Antibody pair set content:
1. Capture antibody: mouse monoclonal anti-IL4R, IgG2a Kappa (100 ug)
2. Detection antibody: biotinylated mouse monoclonal anti-IL4R, IgG2a Kappa (50 ug)
*Reagents are sufficient for at least 3-5 x 96 well plates using recommended protocols.Storage Instruction
Store reagents of the antibody pair set at -20°C or lower. Please aliquot to avoid repeated freeze thaw cycle. Reagents should be returned to -20°C storage immediately after use.
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Applications
ELISA Pair (Recombinant protein)
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Gene Info — IL4R
Entrez GeneID
3566Gene Name
IL4R
Gene Alias
CD124, IL4RA
Gene Description
interleukin 4 receptor
Gene Ontology
HyperlinkGene Summary
This gene encodes the alpha chain of the interleukin-4 receptor, a type I transmembrane protein that can bind interleukin 4 and interleukin 13 to regulate IgE production. The encoded protein also can bind interleukin 4 to promote differentiation of Th2 cells. A soluble form of the encoded protein can be produced by an alternate splice variant or by proteolysis of the membrane-bound protein, and this soluble form can inhibit IL4-mediated cell proliferation and IL5 upregulation by T-cells. Allelic variations in this gene have been associated with atopy, a condition that can manifest itself as allergic rhinitis, sinusitus, asthma, or eczema. Two transcript variants encoding different isoforms, a membrane-bound and a soluble form, have been found for this gene. [provided by RefSeq
Other Designations
OTTHUMP00000122506|interleukin 4 receptor alpha chain|interleukin-4 receptor alpha chain
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