IL1RN MaxPab rabbit polyclonal antibody (D01)
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More Files
- More Functions
Western Blot (Transfected lysate)
Western Blot analysis of IL1RN expression in transfected 293T cell line (H00003557-T02) by IL1RN MaxPab polyclonal antibody.
Lane 1: IL1RN transfected lysate(20.1 KDa).
Lane 2: Non-transfected lysate.
Immunoprecipitation
Immunoprecipitation of IL1RN transfected lysate using anti-IL1RN MaxPab rabbit polyclonal antibody and Protein A Magnetic Bead, and immunoblotted with IL1RN purified MaxPab mouse polyclonal antibody (B01P) (H00003557-B01P).
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Specification
Product Description
Rabbit polyclonal antibody raised against a full-length human IL1RN protein.
Immunogen
IL1RN (NP_776214.1, 1 a.a. ~ 177 a.a) full-length human protein.
Sequence
MEICRGLRSHLITLLLFLFHSETICRPSGRKSSKMQAFRIWDVNQKTFYLRNNQLVAGYLQGPNVNLEEKIDVVPIEPHALFLGIHGGKMCLSCVKSGDETRLQLEAVNITDLSENRKQDKRFAFIRSDSGPTTSFESAACPGWFLCTAMEADQPVSLTNMPDEGVMVTKFYFQEDE
Host
Rabbit
Reactivity
Human
Interspecies Antigen Sequence
Mouse (73); Rat (74)
Quality Control Testing
Antibody reactive against mammalian transfected lysate.
Storage Buffer
No additive
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Transfected lysate)
Western Blot analysis of IL1RN expression in transfected 293T cell line (H00003557-T02) by IL1RN MaxPab polyclonal antibody.
Lane 1: IL1RN transfected lysate(20.1 KDa).
Lane 2: Non-transfected lysate.
Immunoprecipitation
Immunoprecipitation of IL1RN transfected lysate using anti-IL1RN MaxPab rabbit polyclonal antibody and Protein A Magnetic Bead, and immunoblotted with IL1RN purified MaxPab mouse polyclonal antibody (B01P) (H00003557-B01P). -
Gene Info — IL1RN
Entrez GeneID
3557GeneBank Accession#
NM_173842.1Protein Accession#
NP_776214.1Gene Name
IL1RN
Gene Alias
ICIL-1RA, IL-1ra3, IL1F3, IL1RA, IRAP, MGC10430
Gene Description
interleukin 1 receptor antagonist
Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is a member of the interleukin 1 cytokine family. This protein inhibits the activities of interleukin 1, alpha (IL1A) and interleukin 1, beta (IL1B), and modulates a variety of interleukin 1 related immune and inflammatory responses. This gene and five other closely related cytokine genes form a gene cluster spanning approximately 400 kb on chromosome 2. A polymorphism of this gene is reported to be associated with increased risk of osteoporotic fractures and gastric cancer. Four alternatively spliced transcript variants encoding distinct isoforms have been reported. [provided by RefSeq
Other Designations
IL1RN (IL1F3)|intracellular IL-1 receptor antagonist type II|intracellular interleukin-1 receptor antagonist (icIL-1ra)|type II interleukin-1 receptor antagonist
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Interactome
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Disease
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