CYR61 rabbit monoclonal antibody
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Specification
Product Description
Rabbit monoclonal antibody raised against a human CYR61 peptide using ARM Technology.
Immunogen
A synthetic peptide of human CYR61 is used for rabbit immunization.
Customer or Abnova will decide on the preferred peptide sequence.Host
Rabbit
Library Construction
Non-fusion antibody library from rabbit spleen (ARM Technology).
Expression
Overexpression vector and transfection into 293H cell line.
Reactivity
Human
Purification
Protein A
Isotype
IgG
Quality Control Testing
Antibody reactive against human CYR61 peptide by ELISA and mammalian transfected lysate by Western Blot.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
Deliverable
Up to three rabbit IgG clones of 100 ug each will be delivered to customer.
Note
1. Customer may provide cell or tissue lysate for antibody screening.
2. Rabbit monoclonal antibody generated by ARM technology is amenable to antibody engineering including F(ab)2, IgG, scFv and different Fc and non-Fc conjugates per customer request. -
Applications
Western Blot (Transfected lysate)
ELISA
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Gene Info — CYR61
Entrez GeneID
3491GeneBank Accession#
CYR61Gene Name
CYR61
Gene Alias
CCN1, GIG1, IGFBP10
Gene Description
cysteine-rich, angiogenic inducer, 61
Omim ID
602369Gene Ontology
HyperlinkGene Summary
CYR61 is a secreted, cysteine-rich, heparin-binding protein encoded by a growth factor-inducible immediate-early gene. Acting as an extracellular, matrix-associated signaling molecule, CYR61 promotes the adhesion of endothelial cells through interaction with integrin and augments growth factor-induced DNA synthesis in the same cell type.[supplied by OMIM
Other Designations
OTTHUMP00000012303|cysteine-rich heparin-binding protein 61|cysteine-rich, anigogenic inducer, 61
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