IFNGR1 rabbit monoclonal antibody
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Specification
Product Description
Rabbit monoclonal antibody raised against a human IFNGR1 peptide using ARM Technology.
Immunogen
A synthetic peptide of human IFNGR1 is used for rabbit immunization.
Customer or Abnova will decide on the preferred peptide sequence.Host
Rabbit
Library Construction
Non-fusion antibody library from rabbit spleen (ARM Technology).
Expression
Overexpression vector and transfection into 293H cell line.
Reactivity
Human
Purification
Protein A
Isotype
IgG
Quality Control Testing
Antibody reactive against human IFNGR1 peptide by ELISA and mammalian transfected lysate by Western Blot.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
Deliverable
Up to three rabbit IgG clones of 100 ug each will be delivered to customer.
Note
1. Customer may provide cell or tissue lysate for antibody screening.
2. Rabbit monoclonal antibody generated by ARM technology is amenable to antibody engineering including F(ab)2, IgG, scFv and different Fc and non-Fc conjugates per customer request. -
Applications
Western Blot (Transfected lysate)
ELISA
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Gene Info — IFNGR1
Entrez GeneID
3459GeneBank Accession#
IFNGR1Gene Name
IFNGR1
Gene Alias
CD119, FLJ45734, IFNGR
Gene Description
interferon gamma receptor 1
Gene Ontology
HyperlinkGene Summary
This gene (IFNGR1) encodes the ligand-binding chain (alpha) of the gamma interferon receptor. Human interferon-gamma receptor is a heterodimer of IFNGR1 and IFNGR2. A genetic variation in IFNGR1 is associated with susceptibility to Helicobacter pylori infection. In addition, defects in IFNGR1 are a cause of mendelian susceptibility to mycobacterial disease, also known as familial disseminated atypical mycobacterial infection. [provided by RefSeq
Other Designations
AVP, type 2|CD119 antigen|OTTHUMP00000017285|antiviral protein, type 2|immune interferon receptor 1|interferon-gamma receptor alpha chain
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