IFNAR2 (Human) Recombinant Protein (Q01)
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Specification
Product Description
Human IFNAR2 partial ORF ( NP_997468.1, 144 a.a. - 243 a.a.) recombinant protein with GST-tag at N-terminal.
Sequence
FTNHINVMVKFPSIVEEELQFDLSLVIEEQSEGIVKKHKPEIKGNMSGNFTYIIDKLIPNTNYCVSVYLEHSDEQAVIKSPLKCTLLPPGQESESAESAK
Host
Wheat Germ (in vitro)
Theoretical MW (kDa)
36.74
Preparation Method
Purification
Glutathione Sepharose 4 Fast Flow
Quality Control Testing
12.5% SDS-PAGE Stained with Coomassie Blue.
Storage Buffer
50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
Note
Best use within three months from the date of receipt of this protein.
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Applications
Enzyme-linked Immunoabsorbent Assay
Western Blot (Recombinant protein)
Antibody Production
Protein Array
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Gene Info — IFNAR2
Entrez GeneID
3455GeneBank Accession#
NM_207585Protein Accession#
NP_997468.1Gene Name
IFNAR2
Gene Alias
IFN-R, IFN-alpha-REC, IFNABR, IFNARB
Gene Description
interferon (alpha, beta and omega) receptor 2
Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is a type I membrane protein that forms one of the two chains of a receptor for interferons alpha and beta. Binding and activation of the receptor stimulates Janus protein kinases, which in turn phosphorylate several proteins, including STAT1 and STAT2. Multiple transcript variants encoding at least two different isoforms have been found for this gene. [provided by RefSeq
Other Designations
OTTHUMP00000067674|OTTHUMP00000067676|human interferon alpha/beta receptor|interferon alpha/beta receptor 2|interferon-alpha/beta receptor beta chain|type I interferon receptor
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Interactome
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Disease
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