IFNAR2 rabbit monoclonal antibody
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Specification
Product Description
Rabbit monoclonal antibody raised against a human IFNAR2 peptide using ARM Technology.
Immunogen
A synthetic peptide of human IFNAR2 is used for rabbit immunization.
Customer or Abnova will decide on the preferred peptide sequence.Host
Rabbit
Library Construction
Non-fusion antibody library from rabbit spleen (ARM Technology).
Expression
Overexpression vector and transfection into 293H cell line.
Reactivity
Human
Purification
Protein A
Isotype
IgG
Quality Control Testing
Antibody reactive against human IFNAR2 peptide by ELISA and mammalian transfected lysate by Western Blot.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
Deliverable
Up to three rabbit IgG clones of 100 ug each will be delivered to customer.
Note
1. Customer may provide cell or tissue lysate for antibody screening.
2. Rabbit monoclonal antibody generated by ARM technology is amenable to antibody engineering including F(ab)2, IgG, scFv and different Fc and non-Fc conjugates per customer request. -
Applications
Western Blot (Transfected lysate)
ELISA
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Gene Info — IFNAR2
Entrez GeneID
3455GeneBank Accession#
IFNAR2Gene Name
IFNAR2
Gene Alias
IFN-R, IFN-alpha-REC, IFNABR, IFNARB
Gene Description
interferon (alpha, beta and omega) receptor 2
Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is a type I membrane protein that forms one of the two chains of a receptor for interferons alpha and beta. Binding and activation of the receptor stimulates Janus protein kinases, which in turn phosphorylate several proteins, including STAT1 and STAT2. Multiple transcript variants encoding at least two different isoforms have been found for this gene. [provided by RefSeq
Other Designations
OTTHUMP00000067674|OTTHUMP00000067676|human interferon alpha/beta receptor|interferon alpha/beta receptor 2|interferon-alpha/beta receptor beta chain|type I interferon receptor
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