SP110 monoclonal antibody (M03), clone 2G10
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More Files
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Western Blot (Cell lysate)
SP110 monoclonal antibody (M03), clone 2G10 Western Blot analysis of SP110 expression in Hela S3 NE ( Cat # L013V3 ).
Sandwich ELISA (Recombinant protein)
Detection limit for recombinant GST tagged SP110 is approximately 0.1ng/ml as a capture antibody.
Immunofluorescence
Immunofluorescence of monoclonal antibody to SP110 on HeLa cell. [antibody concentration 10 ug/ml]
Western Blot detection against Immunogen (37.84 KDa) .
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Specification
Product Description
Mouse monoclonal antibody raised against a partial recombinant SP110.
Immunogen
SP110 (NP_004501, 271 a.a. ~ 380 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Sequence
TPSDKKGKKRKRCIWSTPKRRHKKKSLPRGTASSRHGIQKKLKRVDQVPQKKDDSTCNSTVETRAQKARTECARKSRSEEIIDGTSEMNEGKRSQKTPSTPRRVTQGAAS
Host
Mouse
Reactivity
Human
Interspecies Antigen Sequence
Rat (48)
Isotype
IgG2a Kappa
Quality Control Testing
Antibody Reactive Against Recombinant Protein.
Western Blot detection against Immunogen (37.84 KDa) .
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Cell lysate)
SP110 monoclonal antibody (M03), clone 2G10 Western Blot analysis of SP110 expression in Hela S3 NE ( Cat # L013V3 ).Western Blot (Recombinant protein)
Sandwich ELISA (Recombinant protein)
Detection limit for recombinant GST tagged SP110 is approximately 0.1ng/ml as a capture antibody.ELISA
Immunofluorescence
Immunofluorescence of monoclonal antibody to SP110 on HeLa cell. [antibody concentration 10 ug/ml] -
Gene Info — SP110
Entrez GeneID
3431GeneBank Accession#
NM_004510Protein Accession#
NP_004501Gene Name
SP110
Gene Alias
FLJ22835, IFI41, IFI75, IPR1, VODI
Gene Description
SP110 nuclear body protein
Gene Ontology
HyperlinkGene Summary
The nuclear body is a multiprotein complex that may have a role in the regulation of gene transcription. This gene is a member of the SP100/SP140 family of nuclear body proteins and encodes a leukocyte-specific nuclear body component. The protein can function as an activator of gene transcription and may serve as a nuclear hormone receptor coactivator. In addition, it has been suggested that the protein may play a role in ribosome biogenesis and in the induction of myeloid cell differentiation. Alternative splicing has been observed for this gene and three transcript variants, encoding distinct isoforms, have been identified. [provided by RefSeq
Other Designations
interferon-induced protein 41, 30kD|interferon-induced protein 75, 52kD|phosphoprotein 41|phosphoprotein 75|transcriptional coactivator Sp110
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Interactome
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Disease
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