SP110 rabbit monoclonal antibody
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Specification
Product Description
Rabbit monoclonal antibody raised against a human SP110 peptide using ARM Technology.
Immunogen
A synthetic peptide of human SP110 is used for rabbit immunization.
Customer or Abnova will decide on the preferred peptide sequence.Host
Rabbit
Library Construction
Non-fusion antibody library from rabbit spleen (ARM Technology).
Expression
Overexpression vector and transfection into 293H cell line.
Reactivity
Human
Purification
Protein A
Isotype
IgG
Quality Control Testing
Antibody reactive against human SP110 peptide by ELISA and mammalian transfected lysate by Western Blot.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
Deliverable
Up to three rabbit IgG clones of 100 ug each will be delivered to customer.
Note
1. Customer may provide cell or tissue lysate for antibody screening.
2. Rabbit monoclonal antibody generated by ARM technology is amenable to antibody engineering including F(ab)2, IgG, scFv and different Fc and non-Fc conjugates per customer request. -
Applications
Western Blot (Transfected lysate)
ELISA
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Gene Info — SP110
Entrez GeneID
3431GeneBank Accession#
SP110Gene Name
SP110
Gene Alias
FLJ22835, IFI41, IFI75, IPR1, VODI
Gene Description
SP110 nuclear body protein
Gene Ontology
HyperlinkGene Summary
The nuclear body is a multiprotein complex that may have a role in the regulation of gene transcription. This gene is a member of the SP100/SP140 family of nuclear body proteins and encodes a leukocyte-specific nuclear body component. The protein can function as an activator of gene transcription and may serve as a nuclear hormone receptor coactivator. In addition, it has been suggested that the protein may play a role in ribosome biogenesis and in the induction of myeloid cell differentiation. Alternative splicing has been observed for this gene and three transcript variants, encoding distinct isoforms, have been identified. [provided by RefSeq
Other Designations
interferon-induced protein 41, 30kD|interferon-induced protein 75, 52kD|phosphoprotein 41|phosphoprotein 75|transcriptional coactivator Sp110
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Interactome
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Disease
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