IFI16 rabbit monoclonal antibody
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Specification
Product Description
Rabbit monoclonal antibody raised against a human IFI16 peptide using ARM Technology.
Immunogen
A synthetic peptide of human IFI16 is used for rabbit immunization.
Customer or Abnova will decide on the preferred peptide sequence.Host
Rabbit
Library Construction
Non-fusion antibody library from rabbit spleen (ARM Technology).
Expression
Overexpression vector and transfection into 293H cell line.
Reactivity
Human
Purification
Protein A
Isotype
IgG
Quality Control Testing
Antibody reactive against human IFI16 peptide by ELISA and mammalian transfected lysate by Western Blot.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
Deliverable
Up to three rabbit IgG clones of 100 ug each will be delivered to customer.
Note
1. Customer may provide cell or tissue lysate for antibody screening.
2. Rabbit monoclonal antibody generated by ARM technology is amenable to antibody engineering including F(ab)2, IgG, scFv and different Fc and non-Fc conjugates per customer request. -
Applications
Western Blot (Transfected lysate)
ELISA
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Gene Info — IFI16
Entrez GeneID
3428GeneBank Accession#
IFI16Gene Name
IFI16
Gene Alias
IFNGIP1, MGC9466, PYHIN2
Gene Description
interferon, gamma-inducible protein 16
Omim ID
147586Gene Ontology
HyperlinkGene Summary
This gene encodes a member of the HIN-200 (hematopoietic interferon-inducible nuclear antigens with 200 amino acid repeats) family of cytokines. The encoded protein contains domains involved in DNA binding, transcriptional regulation, and protein-protein interactions. The protein localizes to the nucleoplasm and nucleoli, and interacts with p53 and retinoblastoma-1. It modulates p53 function, and inhibits cell growth in the Ras/Raf signaling pathway. [provided by RefSeq
Other Designations
OTTHUMP00000035192|interferon-gamma induced protein IFI 16|interferon-inducible myeloid differentiation transcriptional activator
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Interactome
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