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IDI1 rabbit monoclonal antibody

  • Catalog # : H00003422-K
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  • Specification
  • Product Description:
  • Rabbit monoclonal antibody raised against a human IDI1 peptide using ARM Technology.
  • Immunogen:
  • A synthetic peptide of human IDI1 is used for rabbit immunization.
    Customer or Abnova will decide on the preferred peptide sequence.
  • Host:
  • Rabbit
  • Reactivity:
  • Human
  • Purification:
  • Protein A
  • Isotype:
  • IgG
  • Quality Control Testing:
  • Antibody reactive against human IDI1 peptide by ELISA and mammalian transfected lysate by Western Blot.
  • Storage Buffer:
  • In 1x PBS, pH 7.4
  • Storage Instruction:
  • Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
  • Note:
  • 1. Customer may provide cell or tissue lysate for antibody screening.
    2. Rabbit monoclonal antibody generated by ARM technology is amenable to antibody engineering including F(ab)2, IgG, scFv and different Fc and non-Fc conjugates per customer request.
  • Library Construction:
  • Non-fusion antibody library from rabbit spleen (ARM Technology).
  • Expression:
  • Overexpression vector and transfection into 293H cell line.
  • Deliverable:
  • Up to three rabbit IgG clones of 1 mg each will be delivered to customer.
  • Applications
  • ELISA
  • Application Image
  • Western Blot (Transfected lysate)
  • ELISA
  • Gene Information
  • Entrez GeneID:
  • 3422
  • GeneBank Accession#:
  • IDI1
  • Gene Name:
  • IDI1
  • Gene Alias:
  • IPP1,IPPI1
  • Gene Description:
  • isopentenyl-diphosphate delta isomerase 1
  • Gene Summary:
  • IDI1 encodes a peroxisomally-localized enzyme that catalyzes the interconversion of isopentenyl diphosphate (IPP) to its highly electrophilic isomer, dimethylallyl diphosphate (DMAPP), which are the substrates for the successive reaction that results in the synthesis of farnesyl diphosphate and, ultimately, cholesterol. It has been shown in peroxisomal deficiency diseases such as Zellweger syndrome and neonatal adrenoleukodystrophy that there is reduction in IPP isomerase activity. [provided by RefSeq
  • Other Designations:
  • IPP isomerase,OTTHUMP00000018951,isopentenyl diphosphate dimethylallyl diphosphate isomerase 1,isopentenyl pyrophosphate isomerase 1,isopentenyl-diphosphate delta isomerase
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