IDH3A purified MaxPab mouse polyclonal antibody (B01P)
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More Files
- More Functions
Western Blot (Tissue lysate)
IDH3A MaxPab polyclonal antibody. Western Blot analysis of IDH3A expression in rat brain.
Western Blot (Cell lysate)
IDH3A MaxPab polyclonal antibody. Western Blot analysis of IDH3A expression in A-431.
Western Blot (Transfected lysate)
Western Blot analysis of IDH3A expression in transfected 293T cell line (H00003419-T01) by IDH3A MaxPab polyclonal antibody.
Lane 1: IDH3A transfected lysate(40.26 KDa).
Lane 2: Non-transfected lysate.
Immunofluorescence
Immunofluorescence of purified MaxPab antibody to IDH3A on HeLa cell. [antibody concentration 10 ug/ml]
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Specification
Product Description
Mouse polyclonal antibody raised against a full-length human IDH3A protein.
Immunogen
IDH3A (NP_005521.1, 1 a.a. ~ 366 a.a) full-length human protein.
Sequence
MAGPAWISKVSRLLGAFHNPKQVTRGFTGGVQTVTLIPGDGIGPEISAAVMKIFDAAKAPIQWEERNVTAIQGPGGKWMIPSEAKESMDKNKMGLKGPLKTPIAAGHPSMNLLLRKTFDLYANVRPCVSIEGYKTPYTDVNIVTIRENTEGEYSGIEHVIVDGVVQSIKLITEGASKRIAEFAFEYARNNHRSNVTAVHKANIMRMSDGLFLQKCREVAESCKDIKFNEMYLDTVCLNMVQDPSQFDVLVMPNLYGDILSDLCAGLIGGLGVTPSGNIGANGVAIFESVHGTAPDIAGKDMANPTALLLSAVMMLRHMGLFDHAARIEAACFATIKDGKSLTKDLGGNAKCSDFTEEICRRVKDLD
Host
Mouse
Reactivity
Human, Rat
Quality Control Testing
Antibody reactive against mammalian transfected lysate.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Tissue lysate)
IDH3A MaxPab polyclonal antibody. Western Blot analysis of IDH3A expression in rat brain.Western Blot (Cell lysate)
IDH3A MaxPab polyclonal antibody. Western Blot analysis of IDH3A expression in A-431.Western Blot (Transfected lysate)
Western Blot analysis of IDH3A expression in transfected 293T cell line (H00003419-T01) by IDH3A MaxPab polyclonal antibody.
Lane 1: IDH3A transfected lysate(40.26 KDa).
Lane 2: Non-transfected lysate.
Immunofluorescence
Immunofluorescence of purified MaxPab antibody to IDH3A on HeLa cell. [antibody concentration 10 ug/ml] -
Gene Info — IDH3A
Entrez GeneID
3419GeneBank Accession#
NM_005530.2Protein Accession#
NP_005521.1Gene Name
IDH3A
Gene Alias
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Gene Description
isocitrate dehydrogenase 3 (NAD+) alpha
Omim ID
601149Gene Ontology
HyperlinkGene Summary
Isocitrate dehydrogenases catalyze the oxidative decarboxylation of isocitrate to 2-oxoglutarate. These enzymes belong to two distinct subclasses, one of which utilizes NAD(+) as the electron acceptor and the other NADP(+). Five isocitrate dehydrogenases have been reported: three NAD(+)-dependent isocitrate dehydrogenases, which localize to the mitochondrial matrix, and two NADP(+)-dependent isocitrate dehydrogenases, one of which is mitochondrial and the other predominantly cytosolic. NAD(+)-dependent isocitrate dehydrogenases catalyze the allosterically regulated rate-limiting step of the tricarboxylic acid cycle. Each isozyme is a heterotetramer that is composed of two alpha subunits, one beta subunit, and one gamma subunit. The protein encoded by this gene is the alpha subunit of one isozyme of NAD(+)-dependent isocitrate dehydrogenase. [provided by RefSeq
Other Designations
H-IDH alpha|NAD(H)-specific isocitrate dehydrogenase alpha subunit|NAD+-specific ICDH|isocitrate dehydrogenase (NAD+) alpha chain|isocitrate dehydrogenase [NAD] subunit alpha, mitochondrial|isocitric dehydrogenase
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Interactome
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Pathway
- Biosynthesis of alkaloids derived from histidine and purine
- Biosynthesis of alkaloids derived from ornithine
- Biosynthesis of alkaloids derived from shikimate pathway
- Biosynthesis of alkaloids derived from terpenoid and polyketide
- Biosynthesis of plant hormones
- Biosynthesis of terpenoids and steroids
- Citrate cycle (TCA cycle)
- Metabolic pathways
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