ID3 (Human) Recombinant Protein (P01)
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Specification
Product Description
Human ID3 full-length ORF ( AAH03107, 1 a.a. - 119 a.a.) recombinant protein with GST-tag at N-terminal.
Sequence
MKALSPVRGCYEAVCCLSERSLAIARGRGKGPAAEEPLSLLDDMNHCYSRLRELVPGVPRGTQLSQVEILQRVIDYILDLQVVLAEPAPGPPDGPHLPIQTAELAPELVISNDKRSFCH
Host
Wheat Germ (in vitro)
Theoretical MW (kDa)
38.72
Interspecies Antigen Sequence
Mouse (96); Rat (97)
Preparation Method
Purification
Glutathione Sepharose 4 Fast Flow
Quality Control Testing
12.5% SDS-PAGE Stained with Coomassie Blue.
Storage Buffer
50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
Note
Best use within three months from the date of receipt of this protein.
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Applications
Enzyme-linked Immunoabsorbent Assay
Western Blot (Recombinant protein)
Antibody Production
Protein Array
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Gene Info — ID3
Entrez GeneID
3399GeneBank Accession#
BC003107..1Protein Accession#
AAH03107Gene Name
ID3
Gene Alias
HEIR-1, bHLHb25
Gene Description
inhibitor of DNA binding 3, dominant negative helix-loop-helix protein
Omim ID
600277Gene Ontology
HyperlinkGene Summary
Members of the ID family of helix-loop-helix (HLH) proteins lack a basic DNA-binding domain and inhibit transcription through formation of nonfunctional dimers that are incapable of binding to DNA.[supplied by OMIM
Other Designations
OTTHUMP00000003263|inhibitor of DNA binding 3
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Interactome
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Pathway
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Disease
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Publication Reference
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PCB153-Induced Overexpression of ID3 Contributes to the Development of Microvascular Lesions.
Das JK, Felty Q.
PLoS One 2014 Aug; 9(8):e104159.
Application:KA, Recombinant protein.
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PCB153-Induced Overexpression of ID3 Contributes to the Development of Microvascular Lesions.
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