ID2 DNAxPab
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Specification
Product Description
Rabbit polyclonal antibody raised against a full-length human ID2 DNA using DNAx™ Immune technology.
Technology
Immunogen
Full-length human DNA
Sequence
MKAFSPVRSVRKNSLSDHSLGISRSKTPVDDPMSLLYNMNDCYSKLKELVPSIPQNKKVSKMEILQHVIDYILDLQIALDSHPTIVSLHHQRPGQNQASRTPLTTLNTDISILSLQASEFPSELMSNDSKALCG
Host
Rabbit
Reactivity
Human
Purification
Protein A
Quality Control Testing
Antibody reactive against mammalian transfected lysate.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Transfected lysate)
Immunofluorescence (Transfected cell)
Flow Cytometry (Transfected cell)
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Gene Info — ID2
Entrez GeneID
3398GeneBank Accession#
NM_002166.4Protein Accession#
NP_002157.2Gene Name
ID2
Gene Alias
GIG8, ID2A, ID2H, MGC26389, bHLHb26
Gene Description
inhibitor of DNA binding 2, dominant negative helix-loop-helix protein
Omim ID
600386Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene belongs to the inhibitor of DNA binding (ID) family, members of which are transcriptional regulators that contain a helix-loop-helix (HLH) domain but not a basic domain. Members of the ID family inhibit the functions of basic helix-loop-helix transcription factors in a dominant-negative manner by suppressing their heterodimerization partners through the HLH domains. This protein may play a role in negatively regulating cell differentiation. A pseudogene has been identified for this gene. [provided by RefSeq
Other Designations
DNA-binding protein inhibitor ID2|OTTHUMP00000140258|cell growth-inhibiting gene 8|helix-loop-helix protein ID2|inhibitor of DNA binding 2|inhibitor of differentiation 2
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Interactome
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Pathway
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Disease
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