IRF8 (Human) Recombinant Protein (Q01)
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More Files
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Specification
Product Description
Human IRF8 partial ORF ( NP_002154, 122 a.a. - 218 a.a.) recombinant protein with GST-tag at N-terminal.
Sequence
LGVATAGCVNEVTEMECGRSEIDELIKEPSVDDYMGMIKRSPSPPEACRSQLLPDWWAQQPSTGVPLVTGYTTYDAHHSAFSQMVISFYYGGKLVGQ
Host
Wheat Germ (in vitro)
Theoretical MW (kDa)
36.41
Interspecies Antigen Sequence
Mouse (86); Rat (85)
Preparation Method
Purification
Glutathione Sepharose 4 Fast Flow
Quality Control Testing
12.5% SDS-PAGE Stained with Coomassie Blue.
Storage Buffer
50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
Note
Best use within three months from the date of receipt of this protein.
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Applications
Enzyme-linked Immunoabsorbent Assay
Western Blot (Recombinant protein)
Antibody Production
Protein Array
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Gene Info — IRF8
Entrez GeneID
3394GeneBank Accession#
NM_002163Protein Accession#
NP_002154Gene Name
IRF8
Gene Alias
H-ICSBP, ICSBP, ICSBP1, IRF-8
Gene Description
interferon regulatory factor 8
Omim ID
601565Gene Ontology
HyperlinkGene Summary
Interferon consensus sequence-binding protein (ICSBP) is a transcription factor of the interferon (IFN) regulatory factor (IRF) family. Proteins of this family are composed of a conserved DNA-binding domain in the N-terminal region and a divergent C-terminal region that serves as the regulatory domain. The IRF family proteins bind to the IFN-stimulated response element (ISRE) and regulate expression of genes stimulated by type I IFNs, namely IFN-alpha and IFN-beta. IRF family proteins also control expression of IFN-alpha and IFN-beta-regulated genes that are induced by viral infection. [provided by RefSeq
Other Designations
interferon consensus sequence binding protein 1
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Interactome
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Disease
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