ICAM4 rabbit monoclonal antibody
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Specification
Product Description
Rabbit monoclonal antibody raised against a human ICAM4 peptide using ARM Technology.
Immunogen
A synthetic peptide of human ICAM4 is used for rabbit immunization.
Customer or Abnova will decide on the preferred peptide sequence.Host
Rabbit
Library Construction
Non-fusion antibody library from rabbit spleen (ARM Technology).
Expression
Overexpression vector and transfection into 293H cell line.
Reactivity
Human
Purification
Protein A
Isotype
IgG
Quality Control Testing
Antibody reactive against human ICAM4 peptide by ELISA and mammalian transfected lysate by Western Blot.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
Deliverable
Up to three rabbit IgG clones of 100 ug each will be delivered to customer.
Note
1. Customer may provide cell or tissue lysate for antibody screening.
2. Rabbit monoclonal antibody generated by ARM technology is amenable to antibody engineering including F(ab)2, IgG, scFv and different Fc and non-Fc conjugates per customer request. -
Applications
Western Blot (Transfected lysate)
ELISA
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Gene Info — ICAM4
Entrez GeneID
3386GeneBank Accession#
ICAM4Gene Name
ICAM4
Gene Alias
CD242, LW
Gene Description
intercellular adhesion molecule 4 (Landsteiner-Wiener blood group)
Omim ID
111250Gene Ontology
HyperlinkGene Summary
This gene encodes the Landsteiner-Wiener (LW) blood group antigen(s) that belongs to the immunoglobulin (Ig) superfamily, and that shares similarity with the intercellular adhesion molecule (ICAM) protein family. This ICAM protein contains 2 Ig-like C2-type domains and binds to the leukocyte adhesion LFA-1 protein. The molecular basis of the LW(A)/LW(B) blood group antigens is a single aa variation at position 100; Gln-100=LW(A) and Arg-100=LW(B). Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq
Other Designations
CD242 antigen|Landsteiner-Wiener blood group antigen a|Landsteiner-Wiener blood group glycoprotein|intercellular adhesion molecule 4|intercellular adhesion molecule 4 (LW blood group)
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Interactome
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Disease
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