ICA1 rabbit monoclonal antibody
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Specification
Product Description
Rabbit monoclonal antibody raised against a human ICA1 peptide using ARM Technology.
Immunogen
A synthetic peptide of human ICA1 is used for rabbit immunization.
Customer or Abnova will decide on the preferred peptide sequence.Host
Rabbit
Library Construction
Non-fusion antibody library from rabbit spleen (ARM Technology).
Expression
Overexpression vector and transfection into 293H cell line.
Reactivity
Human
Purification
Protein A
Isotype
IgG
Quality Control Testing
Antibody reactive against human ICA1 peptide by ELISA and mammalian transfected lysate by Western Blot.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
Deliverable
Up to three rabbit IgG clones of 100 ug each will be delivered to customer.
Note
1. Customer may provide cell or tissue lysate for antibody screening.
2. Rabbit monoclonal antibody generated by ARM technology is amenable to antibody engineering including F(ab)2, IgG, scFv and different Fc and non-Fc conjugates per customer request. -
Applications
Western Blot (Transfected lysate)
ELISA
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Gene Info — ICA1
Entrez GeneID
3382GeneBank Accession#
ICA1Gene Name
ICA1
Gene Alias
ICA69, ICAp69
Gene Description
islet cell autoantigen 1, 69kDa
Omim ID
147625Gene Ontology
HyperlinkGene Summary
This gene encodes a protein with an arfaptin homology domain that is found both in the cytosol and as membrane-bound form on the Golgi complex and immature secretory granules. This protein is believed to be an autoantigen in insulin-dependent diabetes mellitus and primary Sjogren's syndrome. Alternatively spliced variants which encode different protein isoforms have been described; however, not all variants have been fully characterized. [provided by RefSeq
Other Designations
diabetes mellitus type I autoantigen|islet cell autoantigen 1|islet cell autoantigen 1 (69kD)|islet cell autoantigen 1 isoform|islet cell autoantigen p69
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