HYAL1 (Human) Recombinant Protein (Q01)
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More Files
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Specification
Product Description
Human HYAL1 partial ORF ( NP_009296, 60 a.a. - 159 a.a.) recombinant protein with GST-tag at N-terminal.
Sequence
ANPGQTFRGPDMTIFYSSQLGTYPYYTPTGEPVFGGLPQNASLIAHLARTFQDILAAIPAPDFSGLAVIDWEAWRPRWAFNWDTKDIYRQRSRALVQAQH
Host
Wheat Germ (in vitro)
Theoretical MW (kDa)
36.74
Preparation Method
Purification
Glutathione Sepharose 4 Fast Flow
Quality Control Testing
12.5% SDS-PAGE Stained with Coomassie Blue.
Storage Buffer
50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
Note
Best use within three months from the date of receipt of this protein.
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Applications
Enzyme-linked Immunoabsorbent Assay
Western Blot (Recombinant protein)
Antibody Production
Protein Array
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Gene Info — HYAL1
Entrez GeneID
3373GeneBank Accession#
NM_007312Protein Accession#
NP_009296Gene Name
HYAL1
Gene Alias
HYAL-1, LUCA1, MGC45987, NAT6
Gene Description
hyaluronoglucosaminidase 1
Gene Ontology
HyperlinkGene Summary
This gene encodes a lysosomal hyaluronidase. Hyaluronidases intracellularly degrade hyaluronan, one of the major glycosaminoglycans of the extracellular matrix. Hyaluronan is thought to be involved in cell proliferation, migration and differentiation. This enzyme is active at an acidic pH and is the major hyaluronidase in plasma. Mutations in this gene are associated with mucopolysaccharidosis type IX, or hyaluronidase deficiency. The gene is one of several related genes in a region of chromosome 3p21.3 associated with tumor suppression. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq
Other Designations
hyaluronidase 1|plasma hyaluronidase|tumor suppressor LUCA-1
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Interactome
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Pathway
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Disease
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