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Last updated: 2017/8/20

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HUS1 Pre-design Chimera RNAi

  • Catalog # : H00003364-R01
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  • Specification
  • Product Description:
  • Homo sapiens HUS1 checkpoint homolog (S. pombe) (HUS1), mRNA.
  • Reactivity:
  • Human
  • Supplied Product:
  • DEPC water
  • Target Refseq:
  • NM_004507
  • Storage Instruction:
  • Store at -20°C, do not exceed 4 - 5 freeze-thaw cycles to ensure product integrity.
  • Note:
  • Position of the Chimera RNAi.

  • Publication Reference
  • Applications
  • RNAi Knockdown
  • Application Image
  • RNAi Knockdown
  • Gene Information
  • Entrez GeneID:
  • 3364
  • Gene Name:
  • HUS1
  • Gene Alias:
  • -
  • Gene Description:
  • HUS1 checkpoint homolog (S. pombe)
  • Gene Summary:
  • The protein encoded by this gene is a component of an evolutionarily conserved, genotoxin-activated checkpoint complex that is involved in the cell cycle arrest in response to DNA damage. This protein forms a heterotrimeric complex with checkpoint proteins RAD9 and RAD1. In response to DNA damage, the trimeric complex interacts with another protein complex consisting of checkpoint protein RAD17 and four small subunits of the replication factor C (RFC), which loads the combined complex onto the chromatin. The DNA damage induced chromatin binding has been shown to depend on the activation of the checkpoint kinase ATM, and is thought to be an early checkpoint signaling event. [provided by RefSeq
  • Other Designations:
  • HUS1 checkpoint protein,hus1+-like protein
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