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Last updated: 2016/10/23
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HUS1 purified MaxPab mouse polyclonal antibody (B01P)MaxPab

  • Catalog # : H00003364-B01P
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  • Specification
  • Product Description:
  • Mouse polyclonal antibody raised against a full-length human HUS1 protein.
  • Immunogen:
  • HUS1 (NP_004498, 1 a.a. ~ 280 a.a) full-length human protein.
  • Sequence:
  • Host:
  • Mouse
  • Reactivity:
  • Human
  • Quality Control Testing:
  • Antibody reactive against mammalian transfected lysate.
  • Storage Buffer:
  • In 1x PBS, pH 7.4
  • Storage Instruction:
  • Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
  • Applications
  • Western Blot (Transfected lysate)
  • Western Blot (Transfected lysate)
  • Western Blot analysis of HUS1 expression in transfected 293T cell line (H00003364-T01) by HUS1 MaxPab polyclonal antibody.

    Lane 1: HUS1 transfected lysate(30.8 KDa).
    Lane 2: Non-transfected lysate.
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  • Application Image
  • Western Blot (Transfected lysate)
  • Western Blot (Transfected lysate)
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  • Gene Information
  • Entrez GeneID:
  • 3364
  • Gene Name:
  • HUS1
  • Gene Alias:
  • -
  • Gene Description:
  • HUS1 checkpoint homolog (S. pombe)
  • Gene Summary:
  • The protein encoded by this gene is a component of an evolutionarily conserved, genotoxin-activated checkpoint complex that is involved in the cell cycle arrest in response to DNA damage. This protein forms a heterotrimeric complex with checkpoint proteins RAD9 and RAD1. In response to DNA damage, the trimeric complex interacts with another protein complex consisting of checkpoint protein RAD17 and four small subunits of the replication factor C (RFC), which loads the combined complex onto the chromatin. The DNA damage induced chromatin binding has been shown to depend on the activation of the checkpoint kinase ATM, and is thought to be an early checkpoint signaling event. [provided by RefSeq
  • Other Designations:
  • HUS1 checkpoint protein,hus1+-like protein
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