HUS1 purified MaxPab mouse polyclonal antibody (B01P)
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More Files
- More Functions
Western Blot (Transfected lysate)
Western Blot analysis of HUS1 expression in transfected 293T cell line (H00003364-T01) by HUS1 MaxPab polyclonal antibody.
Lane 1: HUS1 transfected lysate(30.8 KDa).
Lane 2: Non-transfected lysate.
Immunofluorescence
Immunofluorescence of purified MaxPab antibody to HUS1 on HeLa cell. [antibody concentration 7 ug/ml]
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Specification
Product Description
Mouse polyclonal antibody raised against a full-length human HUS1 protein.
Immunogen
HUS1 (NP_004498, 1 a.a. ~ 280 a.a) full-length human protein.
Sequence
MKFRAKIVDGACLNHFTRISNMIAKLAKTCTLRISPDKLNFILCDKLANGGVSMWCELEQENFFNEFQMEGVSAENNEIYLELTSENLSRALKTAQNARALKIKLTNKHFPCLTVSVELLSMSSSSRIVTHDIPIKVIPRKLWKDLQEPVVPDPDVSIYLPVLKTMKSVVEKMKNISNHLVIEANLDGELNLKIETELVCVTTHFKDLGNPPLASESTHEDRNVEHMAEVHIDIRKLLQFLAGQQVNPTKALCNIVNNKMVHFDLLHEDVSLQYFIPALS
Host
Mouse
Reactivity
Human
Quality Control Testing
Antibody reactive against mammalian transfected lysate.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Transfected lysate)
Western Blot analysis of HUS1 expression in transfected 293T cell line (H00003364-T01) by HUS1 MaxPab polyclonal antibody.
Lane 1: HUS1 transfected lysate(30.8 KDa).
Lane 2: Non-transfected lysate.
Immunofluorescence
Immunofluorescence of purified MaxPab antibody to HUS1 on HeLa cell. [antibody concentration 7 ug/ml] -
Gene Info — HUS1
Entrez GeneID
3364GeneBank Accession#
NM_004507Protein Accession#
NP_004498Gene Name
HUS1
Gene Alias
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Gene Description
HUS1 checkpoint homolog (S. pombe)
Omim ID
603760Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is a component of an evolutionarily conserved, genotoxin-activated checkpoint complex that is involved in the cell cycle arrest in response to DNA damage. This protein forms a heterotrimeric complex with checkpoint proteins RAD9 and RAD1. In response to DNA damage, the trimeric complex interacts with another protein complex consisting of checkpoint protein RAD17 and four small subunits of the replication factor C (RFC), which loads the combined complex onto the chromatin. The DNA damage induced chromatin binding has been shown to depend on the activation of the checkpoint kinase ATM, and is thought to be an early checkpoint signaling event. [provided by RefSeq
Other Designations
HUS1 checkpoint protein|hus1+-like protein
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Interactome
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Disease
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