HTR5A (Human) Recombinant Protein (Q01)
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Specification
Product Description
Human HTR5A partial ORF ( NP_076917, 223 a.a. - 282 a.a.) recombinant protein with GST-tag at N-terminal.
Sequence
IYKAAKFRVGSRKTNSVSPISEAVEVKDSAKQPQMVFTVRHATVTFQPEGDTWREQKEQR
Host
Wheat Germ (in vitro)
Theoretical MW (kDa)
32.34
Interspecies Antigen Sequence
Mouse (83); Rat (88)
Preparation Method
Purification
Glutathione Sepharose 4 Fast Flow
Quality Control Testing
12.5% SDS-PAGE Stained with Coomassie Blue.
Storage Buffer
50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
Note
Best use within three months from the date of receipt of this protein.
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Applications
Enzyme-linked Immunoabsorbent Assay
Western Blot (Recombinant protein)
Antibody Production
Protein Array
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Gene Info — HTR5A
Entrez GeneID
3361GeneBank Accession#
NM_024012Protein Accession#
NP_076917Gene Name
HTR5A
Gene Alias
5-HT5A, MGC138226
Gene Description
5-hydroxytryptamine (serotonin) receptor 5A
Omim ID
601305Gene Ontology
HyperlinkGene Summary
The neurotransmitter serotonin (5-hydroxytryptamine, 5-HT) has been implicated in a wide range of psychiatric conditions and also has vasoconstrictive and vasodilatory effects. The gene described in this record is a member of 5-hydroxytryptamine (serotonin) receptor family and encodes a multi-pass membrane protein that functions as a receptor for 5-hydroxytryptamine and couples to G-proteins. This protein has been shown to function in part through the regulation of intracellular Ca2+ mobilization. [provided by RefSeq
Other Designations
5-hydroxytryptamine receptor 5A
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Interactome
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Pathway
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Disease
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