HTR4 rabbit monoclonal antibody
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Specification
Product Description
Rabbit monoclonal antibody raised against a human HTR4 peptide using ARM Technology.
Immunogen
A synthetic peptide of human HTR4 is used for rabbit immunization.
Customer or Abnova will decide on the preferred peptide sequence.Host
Rabbit
Library Construction
Non-fusion antibody library from rabbit spleen (ARM Technology).
Expression
Overexpression vector and transfection into 293H cell line.
Reactivity
Human
Purification
Protein A
Isotype
IgG
Quality Control Testing
Antibody reactive against human HTR4 peptide by ELISA and mammalian transfected lysate by Western Blot.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
Deliverable
Up to three rabbit IgG clones of 100 ug each will be delivered to customer.
Note
1. Customer may provide cell or tissue lysate for antibody screening.
2. Rabbit monoclonal antibody generated by ARM technology is amenable to antibody engineering including F(ab)2, IgG, scFv and different Fc and non-Fc conjugates per customer request. -
Applications
Western Blot (Transfected lysate)
ELISA
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Gene Info — HTR4
Entrez GeneID
3360GeneBank Accession#
HTR4Gene Name
HTR4
Gene Alias
5-HT4, 5-HT4R
Gene Description
5-hydroxytryptamine (serotonin) receptor 4
Omim ID
602164Gene Ontology
HyperlinkGene Summary
This gene is a member of the family of serotonin receptors, which are G protein coupled receptors that stimulate cAMP production in response to serotonin (5-hydroxytryptamine). The gene product is a glycosylated transmembrane protein that functions in both the peripheral and central nervous system to modulate the release of various neurotransmitters. Multiple transcript variants encoding proteins with distinct C-terminal sequences have been described, but the full-length nature of some transcript variants has not been determined. [provided by RefSeq
Other Designations
5-hydroxytryptamine4 receptor|cardiac 5-HT4 receptor|serotonin 5-HT4 receptor
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