HTR3A rabbit monoclonal antibody
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Specification
Product Description
Rabbit monoclonal antibody raised against a human HTR3A peptide using ARM Technology.
Immunogen
A synthetic peptide of human HTR3A is used for rabbit immunization.
Customer or Abnova will decide on the preferred peptide sequence.Host
Rabbit
Library Construction
Non-fusion antibody library from rabbit spleen (ARM Technology).
Expression
Overexpression vector and transfection into 293H cell line.
Reactivity
Human
Purification
Protein A
Isotype
IgG
Quality Control Testing
Antibody reactive against human HTR3A peptide by ELISA and mammalian transfected lysate by Western Blot.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
Deliverable
Up to three rabbit IgG clones of 100 ug each will be delivered to customer.
Note
1. Customer may provide cell or tissue lysate for antibody screening.
2. Rabbit monoclonal antibody generated by ARM technology is amenable to antibody engineering including F(ab)2, IgG, scFv and different Fc and non-Fc conjugates per customer request. -
Applications
Western Blot (Transfected lysate)
ELISA
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Gene Info — HTR3A
Entrez GeneID
3359GeneBank Accession#
HTR3AGene Name
HTR3A
Gene Alias
5-HT-3, 5-HT3A, 5-HT3R, 5HT3R, HTR3
Gene Description
5-hydroxytryptamine (serotonin) receptor 3A
Omim ID
182139Gene Ontology
HyperlinkGene Summary
The product of this gene belongs to the ligand-gated ion channel receptor superfamily. This gene encodes subunit A of the type 3 receptor for 5-hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. This receptor causes fast, depolarizing responses in neurons after activation. It appears that the heteromeric combination of A and B subunits is necessary to provide the full functional features of this receptor, since either subunit alone results in receptors with very low conductance and response amplitude. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq
Other Designations
5-hydroxytryptamine (serotonin) receptor-3|5HT3 serotonin receptor|serotonin receptor|serotonin-gated ion channel receptor
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Interactome
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Disease
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