HTR1B polyclonal antibody (A01)
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Specification
Product Description
Mouse polyclonal antibody raised against a partial recombinant HTR1B.
Immunogen
HTR1B (NP_000854, 1 a.a. ~ 49 a.a) partial recombinant protein with GST tag.
Sequence
MEEPGAQCAPPPPAGSETWVPQANLSSAPSQNCSAKDYIYQDSISLPWK
Host
Mouse
Reactivity
Human
Interspecies Antigen Sequence
Mouse (69); Rat (73)
Quality Control Testing
Antibody Reactive Against Recombinant Protein.
Western Blot detection against Immunogen (31.5 KDa) .
Storage Buffer
50 % glycerol
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Recombinant protein)
ELISA
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Gene Info — HTR1B
Entrez GeneID
3351GeneBank Accession#
NM_000863Protein Accession#
NP_000854Gene Name
HTR1B
Gene Alias
5-HT1B, 5-HT1DB, HTR1D2, HTR1DB, S12
Gene Description
5-hydroxytryptamine (serotonin) receptor 1B
Omim ID
182131Gene Ontology
HyperlinkGene Summary
The neurotransmitter serotonin (5-hydroxytryptamine; 5-HT) exerts a wide variety of physiologic functions through a multiplicity of receptors and may be involved in human neuropsychiatric disorders such as anxiety, depression, or migraine. These receptors consist of 4 main groups, 5-HT-1, 5-HT-2, 5-HT-3, and 5-HT4, subdivided into several distinct subtypes on the basis of their pharmacologic characteristics, coupling to intracellular second messengers, and distribution within the nervous system (Zifa and Fillion, 1992 [PubMed 1359584]). The serotonergic receptors belong to the multigene family of receptors coupled to guanine nucleotide-binding proteins.[supplied by OMIM
Other Designations
OTTHUMP00000016769
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Interactome
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Pathway
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Disease
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Publication Reference
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A Noncanonical Postsynaptic Transport Route for a GPCR Belonging to the Serotonin Receptor Family.
Liebmann T, Kruusmagi M, Sourial-Bassillious N, Bondar A, Svenningsson P, Flajolet M, Greengard P, Scott L, Brismar H, Aperia A.
Journal of Neuroscience 2012 Dec; 32(50):17998.
Application:WB-Ti, IP, IF, Rat, Hippocampal tissue.
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A Noncanonical Postsynaptic Transport Route for a GPCR Belonging to the Serotonin Receptor Family.
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