Proximity Ligation Analysis of protein-protein interactions between HSPA1L and TP53. HeLa cells were stained with anti-HSPA1L rabbit purified polyclonal 1:1200 and anti-TP53 mouse monoclonal antibody 1:50. Each red dot represents the detection of protein-protein interaction complex, and nuclei were counterstained with DAPI (blue).
This gene encodes a 70kDa heat shock protein. In conjunction with other heat shock proteins, this protein stabilizes existing proteins against aggregation and mediates the folding of newly translated proteins in the cytosol and in organelles. The gene is located in the major histocompatibility complex class III region, in a cluster with two closely related genes which also encode isoforms of the 70kDa heat shock protein. [provided by RefSeq
OTTHUMP00000029295,heat shock 10kDa protein 1-like,heat shock 70kD protein-like 1