HSD17B3 DNAxPab
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Specification
Product Description
Rabbit polyclonal antibody raised against a full-length human HSD17B3 DNA using DNAx™ Immune technology.
Technology
Immunogen
Full-length human DNA
Sequence
MGDVLEQFFILTGLLVCLACLAKCVRFSRCVLLNYWKVLPKSFLRSMGQWAVITGAGDGIGKAYSFELAKRGLNVVLISRTLEKLEAIATEIERTTGRSVKIIQADFTKDDIYEHIKEKLAGLEIGILVNNVGMLPNLLPSHFLNAPDEIQSLIHCNITSVVKMTQLILKHMESRQKGLILNISSGIALFPWPLYSMYSASKAFVCAFSKALQEEYKAKEVIIQVLTPYAVSTAMTKYLNTNVITKTADEFVKESLNYVTIGGETCGCLAHEILAGFLSLIPAWAFYSGAFQRLLLTHYVAYLKLNTKVR
Host
Rabbit
Reactivity
Human
Purification
Protein A
Quality Control Testing
Antibody reactive against mammalian transfected lysate.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Transfected lysate)
Immunofluorescence (Transfected cell)
Flow Cytometry (Transfected cell)
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Gene Info — HSD17B3
Entrez GeneID
3293GeneBank Accession#
NM_000197.1Protein Accession#
NP_000188.1Gene Name
HSD17B3
Gene Alias
EDH17B3, SDR12C2
Gene Description
hydroxysteroid (17-beta) dehydrogenase 3
Gene Ontology
HyperlinkGene Summary
This isoform of 17 beta-hydroxysteroid dehydrogenase is expressed predominantly in the testis and catalyzes the conversion of androstenedione to testosterone. It preferentially uses NADP as cofactor. Deficiency can result in male pseudohermaphroditism with gynecomastia. [provided by RefSeq
Other Designations
17-beta-HSD3|OTTHUMP00000021718|estradiol 17 beta-dehydrogenase 3|short chain dehydrogenase/reductase family 12C, member 2
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Interactome
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Pathway
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Disease
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