HSD17B3 (Human) Recombinant Protein (P01)
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Specification
Product Description
Human HSD17B3 full-length ORF ( NP_000188.1, 1 a.a. - 310 a.a.) recombinant protein with GST-tag at N-terminal.
Sequence
MGDVLEQFFILTGLLVCLACLAKCVRFSRCVLLNYWKVLPKSFLRSMGQWAVITGAGDGIGKAYSFELAKRGLNVVLISRTLEKLEAIATEIERTTGRSVKIIQADFTKDDIYEHIKEKLAGLEIGILVNNVGMLPNLLPSHFLNAPDEIQSLIHCNITSVVKMTQLILKHMESRQKGLILNISSGIALFPWPLYSMYSASKAFVCAFSKALQEEYKAKEVIIQVLTPYAVSTAMTKYLNTNVITKTADEFVKESLNYVTIGGETCGCLAHEILAGFLSLIPAWAFYSGAFQRLLLTHYVAYLKLNTKVR
Host
Wheat Germ (in vitro)
Theoretical MW (kDa)
60.9
Preparation Method
Purification
Glutathione Sepharose 4 Fast Flow
Quality Control Testing
12.5% SDS-PAGE Stained with Coomassie Blue.
Storage Buffer
50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
Note
Best use within three months from the date of receipt of this protein.
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Applications
Enzyme-linked Immunoabsorbent Assay
Western Blot (Recombinant protein)
Antibody Production
Protein Array
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Gene Info — HSD17B3
Entrez GeneID
3293GeneBank Accession#
NM_000197.1Protein Accession#
NP_000188.1Gene Name
HSD17B3
Gene Alias
EDH17B3, SDR12C2
Gene Description
hydroxysteroid (17-beta) dehydrogenase 3
Gene Ontology
HyperlinkGene Summary
This isoform of 17 beta-hydroxysteroid dehydrogenase is expressed predominantly in the testis and catalyzes the conversion of androstenedione to testosterone. It preferentially uses NADP as cofactor. Deficiency can result in male pseudohermaphroditism with gynecomastia. [provided by RefSeq
Other Designations
17-beta-HSD3|OTTHUMP00000021718|estradiol 17 beta-dehydrogenase 3|short chain dehydrogenase/reductase family 12C, member 2
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Interactome
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Pathway
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Disease
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