HSD11B1 293T Cell Transient Overexpression Lysate(Denatured)
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Specification
Transfected Cell Line
293T
Plasmid
pCMV-HSD11B1 full-length
Host
Human
Theoretical MW (kDa)
32.23
Quality Control Testing
Transient overexpression cell lysate was tested with Anti-HSD11B1 antibody (H00003290-B01) by Western Blots.
SDS-PAGE Gel
HSD11B1 transfected lysate.
Western Blot
Lane 1: HSD11B1 transfected lysate ( 32.23 KDa)
Lane 2: Non-transfected lysate.Storage Buffer
1X Sample Buffer (50 mM Tris-HCl, 2% SDS, 10% glycerol, 300 mM 2-mercaptoethanol, 0.01% Bromophenol blue)
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot
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Gene Info — HSD11B1
Entrez GeneID
3290GeneBank Accession#
NM_005525.2Protein Accession#
-Gene Name
HSD11B1
Gene Alias
11-DH, 11-beta-HSD1, HDL, HSD11, HSD11B, HSD11L, MGC13539, SDR26C1
Gene Description
hydroxysteroid (11-beta) dehydrogenase 1
Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is a microsomal enzyme that catalyzes the conversion of the stress hormone cortisol to the inactive metabolite cortisone. In addition, the encoded protein can catalyze the reverse reaction, the conversion of cortisone to cortisol. Too much cortisol can lead to central obesity, and a particular variation in this gene has been associated with obesity and insulin resistance in children. Two transcript variants encoding the same protein have been found for this gene. [provided by RefSeq
Other Designations
11-beta-hydroxysteroid dehydrogenase 1|OTTHUMP00000034649|OTTHUMP00000034650|corticosteroid 11-beta-dehydrogenase isozyme 1|short chain dehydrogenase/reductase family 26C, member 1
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Interactome
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Pathway
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Disease
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