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Last updated: 2016/10/23

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HPS1 rabbit monoclonal antibody

  • Catalog # : H00003257-K
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  • Specification
  • Product Description:
  • Rabbit monoclonal antibody raised against a human HPS1 peptide using ARM Technology.
  • Immunogen:
  • A synthetic peptide of human HPS1 is used for rabbit immunization.
    Customer or Abnova will decide on the preferred peptide sequence.
  • Host:
  • Rabbit
  • Reactivity:
  • Human
  • Purification:
  • Protein A
  • Isotype:
  • IgG
  • Quality Control Testing:
  • Antibody reactive against human HPS1 peptide by ELISA and mammalian transfected lysate by Western Blot.
  • Storage Buffer:
  • In 1x PBS, pH 7.4
  • Storage Instruction:
  • Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
  • Note:
  • 1. Customer may provide cell or tissue lysate for antibody screening.
    2. Rabbit monoclonal antibody generated by ARM technology is amenable to antibody engineering including F(ab)2, IgG, scFv and different Fc and non-Fc conjugates per customer request.
  • Library Construction:
  • Non-fusion antibody library from rabbit spleen (ARM Technology).
  • Expression:
  • Overexpression vector and transfection into 293H cell line.
  • Deliverable:
  • Up to three rabbit IgG clones of 1 mg each will be delivered to customer.
  • Applications
  • Application Image
  • Western Blot (Transfected lysate)
  • Gene Information
  • Entrez GeneID:
  • 3257
  • GeneBank Accession#:
  • HPS1
  • Gene Name:
  • HPS1
  • Gene Alias:
  • HPS,MGC5277
  • Gene Description:
  • Hermansky-Pudlak syndrome 1
  • Gene Summary:
  • This gene encodes a protein that may play a role in organelle biogenesis associated with melanosomes, platelet dense granules, and lysosomes. The encoded protein is a component of three different protein complexes termed biogenesis of lysosome-related organelles complex (BLOC)-3, BLOC4, and BLOC5. Mutations in this gene are associated with Hermansky-Pudlak syndrome type 1. Multiple transcript variants encoding distinct isoforms have been identified for this gene; the full-length sequences of some of these have not been determined yet. [provided by RefSeq
  • Other Designations:
  • Hermansky-Pudlak syndrome 1 protein,Hermansky-Pudlak syndrome type 1,OTTHUMP00000020245,OTTHUMP00000020246
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